Cassie A Barton, Heath J Oetken, Nicolas L Hall, Michael Kolesnikov, Elizabeth S Levins, Thomas Sutton, Martin Schreiber
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引用次数: 0
摘要
创伤中心越来越多地使用全血(WB)复苏。之前对全血复苏与纯成分复苏(CO)结果进行的调查研究因队列规模小、全血复苏量低、CO复苏不平衡而受到限制。本研究旨在利用一个大容量 I 级创伤中心的数据来解决这些局限性,该中心于 2018 年采用了 WB 优先复苏模式。我们假设复苏方法(WB 或平衡 CO)对患者死亡率没有影响。
Whole blood versus balanced resuscitation in massive hemorrhage: six of one or half dozen of the other?
Whole blood (WB) resuscitation is increasingly used at trauma centers. Prior studies investigating outcomes in WB versus component-only (CO) resuscitation have been limited by small cohorts, low volumes of WB resuscitation, and unbalanced CO resuscitation. This study aimed to address these limitations using data from a high-volume Level I trauma center, which adopted a WB-first resuscitation paradigm in 2018. We hypothesized that the resuscitation method, WB or balanced CO, would have no impact on patient mortality.