由Phaeoacremonium venezuelense引起的皮下噬菌体病：哥斯达黎加首例临床病例报告

IF 1.6 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Medical Mycology Case Reports Pub Date : 2024-04-27 DOI:10.1016/j.mmcr.2024.100650

Mariamalia Cob , Luisa F. López , D. Joseph Sexton , Adrián Fallas , Juan David Muñoz , Ricardo Gutiérrez

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引用次数: 0

摘要

Phaeoacremonium 是一种很少引起人类感染的半知菌属真菌。我们描述了一例皮下感染病例，患者是一名 70 岁的糖尿病患者，一只脚的脚背有病变。我们分离出了病原体，并对其进行了基质辅助激光解吸电离飞行时间质谱分析（MALDI-TOF MS）和 DNA 测序。确诊后，患者接受了囊肿刮除手术，并服用了 100 毫克伊曲康唑，每天两次，持续 6 个月。治疗后，患者的病变得到了临床缓解。这是在哥斯达黎加报告的首例委内瑞拉鞘氨醇感染病例。

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Subcutaneous phaeohyphomycosis due to Phaeoacremonium venezuelense: The first clinical case report in Costa Rica

Phaeoacremonium is a genus of dematiaceous fungi that rarely causes human infections. We describe a case of subcutaneous infection in a 70-year-old diabetic man with lesions on the dorsum of the one foot. The agent was isolated, and for the final identification we performed matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) and DNA sequencing. After diagnosis, the patient underwent curettage of the cyst and received 100mg of Itraconazole, twice daily for 6 months. Clinical resolution of the lesion was observed after treatment. This is the first case of infection by Phaeoacremonium venezuelense reported in Costa Rica.

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来源期刊

Medical Mycology Case Reports MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

4.00

自引率

0.00%

发文量

审稿时长

47 days