拉丁美洲一所大学医院的迷惑综合征(谵妄)发病率。

Gabriel Fernando Oviedo Lugo , Paola Andrea García Martínez , Andrés Duarte Osorio , Carlos Javier Rincón , Alejandra López , Roberto Chavarría , Catalina Pineda Betancur , Natalia García Gil , María Natalia Duarte Ariza , Juan Agustín Patiño Trejos , Juan Sebastián Insignares , Carlos Gómez-Restrepo
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引用次数: 0

摘要

背景对拉丁美洲大学医院不同科室住院患者的谵妄发生率及其亚型知之甚少。 目的确定哥伦比亚波哥大一所大学医院不同科室住院患者的谵妄发生率、亚型发生率及其相关因素。方法 在2018年1月至6月期间,对一家大学医院的内科(IM)、老年病科(GU)、普通外科(GSU)、骨科(OU)和重症监护室(ICU)收治的18岁以上患者进行了队列随访。为了检测是否存在谵妄,我们使用了CAM(意识模糊评估法),如果患者交流能力下降,则使用CAM-ICU。谵妄亚型采用里士满躁动与镇静量表(RASS)进行描述。患者在入院当日接受评估,之后每两天接受一次评估,直至出院。发现谵妄的患者将被转诊至院内跨学科专科进行治疗。谵妄的总发生率为12%(95% CI,0.3-14.8)。谵妄患者中,GU占31.8%,ICU占15.6%,IM占8.7%,OU占5.1%,GSU占3.9%。最常见的临床表现是混合亚型,占 60.9%,其次是正常反应亚型(34.4%)和低反应亚型(4.7%)。与谵妄最相关的因素是年龄(调整后RR=1.07;95% CI,1.05-1.09)、四种或更多合并症(调整后RR=2.04;95% CI,1.31-3.20)和重症监护室患者(调整后RR=2.02;95% CI,1.22-3.35)。谵妄在大学医院不同科室的发病率各不相同。混合亚型是最常见的亚型,主要相关因素包括年龄、四种或更多合并症以及重症监护室患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Incidence of confusional syndrome (delirium) in a Latin American university hospital

Background

Little is known about the incidence of delirium and its subtypes in patients admitted to different departments of university hospitals in Latin America.

Objective

To determine the incidence of delirium and the frequency of its subtypes, as well as its associated factors, in patients admitted to different departments of a university hospital in Bogotá, Colombia.

Methods

A cohort of patients over 18 years of age admitted to the internal medicine (IM), geriatrics (GU), general surgery (GSU), orthopaedics (OU) and intensive care unit (ICU) services of a university hospital was followed up between January and June 2018. To detect the presence of delirium, we used the CAM (Confusion Assessment Method) and the CAM-ICU if the patient had decreased communication skills. The delirium subtype was characterised using the RASS (Richmond Agitation and Sedation Scale). Patients were assessed on their admission date and then every two days until discharged from the hospital. Those in whom delirium was identified were referred for specialised intra-institutional interdisciplinary management.

Results

A total of 531 patients admitted during the period were assessed. The overall incidence of delirium was 12% (95% CI, 0.3–14.8). They represented 31.8% of patients in the GU, 15.6% in the ICU, 8.7% in IM, 5.1% in the OU, and 3.9% in the GSU. The most frequent clinical display was the mixed subtype, at 60.9%, followed by the normoactive subtype (34.4%) and the hypoactive subtype (4.7%). The factors most associated with delirium were age (adjusted RR = 1.07; 95% CI, 1.05−1.09), the presence of four or more comorbidities (adjusted RR = 2.04; 95% CI, 1.31−3.20), and being a patient in the ICU (adjusted RR = 2.02; 95% CI, 1.22−3.35).

Conclusions

The incidence of delirium is heterogeneous in the different departments of the university hospital. The highest incidence occurred in patients that were admitted to the GU. The mixed subtype was the most frequent one, and the main associated factors were age, the presence of four or more comorbidities, and being an ICU patient.

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