对昼夜节律生物学若干里程碑式进展的思考

Q2 Biochemistry, Genetics and Molecular Biology

Journal of Circadian Rhythms Pub Date : 2024-04-01 DOI:10.5334/jcr.236

Sangeeta Chawla, Henrik Oster, Giles E. Duffield, Erik Maronde, Mario E Guido, Christopher Chabot, O. Dkhissi-Benyahya, Ignacio Provencio, Namni Goel, Shawn D. Youngstedt, Natalie Zi-Ching Mak, Mario Caba, Anjoom Nikhat, Shaon Chakrabarti, Lei Wang, Seth J. Davis

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引用次数: 0

摘要

昼夜节律生物学与不同的科学领域相互交叉，错综复杂地交织在生物体生理学和行为学的结构之中。昼夜节律钟对生命节奏的协调是各学科研究人员关注的焦点。这篇回顾性文章深入探讨了从根本上影响我们当代对昼夜节律认识的几个科学里程碑。从破译细胞水平时钟基因的复杂性，到探索整个生物体对刺激反应中耦合振荡器的细微差别。这一领域在遗传学方法的指导下经历了重大演变。我们在此探讨了昼夜节律研究领域的关键时刻，通过对科学进步和范式转变的敏锐观察，阐明了这一学科的发展轨迹。

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Reflections on Several Landmark Advances in Circadian Biology

Circadian Biology intersects with diverse scientific domains, intricately woven into the fabric of organismal physiology and behavior. The rhythmic orchestration of life by the circadian clock serves as a focal point for researchers across disciplines. This retrospective examination delves into several of the scientific milestones that have fundamentally shaped our contemporary understanding of circadian rhythms. From deciphering the complexities of clock genes at a cellular level to exploring the nuances of coupled oscillators in whole organism responses to stimuli. The field has undergone significant evolution lately guided by genetics approaches. Our exploration here considers key moments in the circadian-research landscape, elucidating the trajectory of this discipline with a keen eye on scientific advancements and paradigm shifts.

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来源期刊

Journal of Circadian Rhythms Biochemistry, Genetics and Molecular Biology-Physiology

CiteScore

7.10

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： Journal of Circadian Rhythms is an Open Access, peer-reviewed online journal that publishes research articles dealing with circadian and nycthemeral (daily) rhythms in living organisms, including processes associated with photoperiodism and daily torpor. Journal of Circadian Rhythms aims to include both basic and applied research at any level of biological organization (molecular, cellular, organic, organismal, and populational). Studies of daily rhythms in environmental factors that directly affect circadian rhythms are also pertinent to the journal"s mission.