蛋白拮抗剂的拴系功能

IF 4.3 2区生物学 Q2 CELL BIOLOGY

Cell calcium Pub Date : 2024-04-20 DOI:10.1016/j.ceca.2024.102875

Wei-Yin Lin, Woo Young Chung, Shmuel Muallem

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引用次数: 0

摘要

阳离子维生素的核心功能是 Cl- 通道活性和磷脂酰丝氨酸（或许还有其他脂质）扰乱。这些功能已在各种组织和细胞中得到广泛研究。然而，阳起素的另一种功能是作为膜接触位点的拴系物，但这一功能较少被认识和探索。这篇简短的综述旨在研究支持阳起糖蛋白在膜接触位点定位的证据、它们的系链特性及其作为系链的功能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The tether function of the anoctamins

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The tether function of the anoctamins

The core functions of the anoctamins are Cl⁻ channel activity and phosphatidylserine (and perhaps other lipids) scrambling. These functions have been extensively studied in various tissues and cells. However, another function of the anoctamins that is less recognized and minimally explored is as tethers at membrane contact sites. This short review aims to examine evidence supporting the localization of the anoctamins at membrane contact sites, their tether properties, and their functions as tethers.

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来源期刊

Cell calcium 生物-细胞生物学

CiteScore

8.70

自引率

5.00%

发文量

115

审稿时长

35 days

期刊介绍： Cell Calcium covers the field of calcium metabolism and signalling in living systems, from aspects including inorganic chemistry, physiology, molecular biology and pathology. Topic themes include: Roles of calcium in regulating cellular events such as apoptosis, necrosis and organelle remodelling Influence of calcium regulation in affecting health and disease outcomes