在光子和电子束放射治疗中使用多晶铯铽相对剂量计的可行性评估

S.W. Yang, S. Park, K.H. Kim
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引用次数: 0

摘要

容积调制弧治疗是放射治疗领域的最新技术。它涉及对多叶准直器的空间分布、剂量率和龙门旋转速度进行连续调节,因此需要一种具有高空间分辨率和单位体积超灵敏度的剂量计。特别是,铯基无机过氧化物已经被研究用于从光电导太阳能电池到辐射探测器的各种应用。这些过氧化物以其出色的特性而闻名,包括热稳定性、无机稳定性和光吸收能力。尽管 CsPbI3 材料具有这些优势特性,但目前仅在放射诊断方面进行了研究,在放射治疗方面的探索还很有限。为了弥补这一空白,本研究验证了 CsPbI3 材料(因其出色的辐射探测效率而闻名)作为能够测量放疗设备辐射探测性能的剂量计的可行性。在直线加速器中应用光子和电子束时,对其再现性、线性度和深度剂量百分比(PDD)进行了评估。再现性评估结果令人印象深刻,在电子束能量为 6、9 和 12 MeV 时,相对标准偏差分别为 0.53%、0.32% 和 0.38%;在光子束能量为 6 和 15 MV 时,相对标准偏差分别为 0.45% 和 0.89%。此外,线性测试显示,在 6、9 和 12 MeV 以及 6 和 15 MV 下,R 2 值为 0.9999,表明线性度很高。为本研究制作的铯硼硅酸盐剂量计绘制的 PDD 图显示,D 最大点是一致的。新型 CsPbI3 剂量计的检测性能达到了所有标准:再现性、线性和 PDD。这些结果共同表明,掺铒晶体剂量计可用于放射治疗设备中的剂量计。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Feasibility assessment of polycrystalline CsPbI3 relative dosimeters in photon and electron beam radiotherapy
Volumetric modulated arc therapy represents the latest technology in radiotherapy. It involves continuous modification of the multi-leaf collimator spatial distribution, dose rate, and gantry rotational speed, necessitating a dosimeter with high spatial resolution and exceptional sensitivity per unit volume. In particular, cesium-based inorganic perovskites have been studied for various applications, spanning from photoconductor solar cells to radiation detectors. These perovskites are renowned for their outstanding attributes, including thermal stability, inorganic stability, and light absorption capacity. Despite such advantageous characteristics, CsPbI3 materials have only been investigated in radiodiagnostics, with limited exploration in radiotherapy. To address this gap, this study verified the viability of CsPbI3  materials, note for their outstanding radiation detection efficiency, as dosimeters capable of measuring the radiation detection performance for radiotherapy devices. The reproducibility, linearity, and percent depth dose (PDD) were evaluated under the application of photon and electron beams in linear accelerators. The reproducibility assessment revealed impressive results, with the relative standard deviation registering at 0.53%, 0.32%, and 0.38% under electron beam energies of 6, 9, and 12 MeV and 0.45%, and 0.89% under photon beam energies of 6 and 15 MV. Moreover, the linearity test revealed an R 2 value of 0.9999, indicating high linearity, at 6, 9, and 12 MeV and at 6 and 15 MV. The PDD graphs drawn for the CsPbI3 dosimeter fabricated in this study showed that the D max points were consistent. The novel CsPbI3 dosimeter demonstrated a level of detection performance that satisfied all criteria; reproducibility, linearity, and PDD. The results collectively indicated that the CsPbI3  dosimeter can be used for dosimeters in radiotherapy devices.
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