运动/感觉混合神经重建中的神经自体移植与异体移植

Q3 Medicine

Journal of Hand Surgery Global Online Pub Date : 2024-09-01 DOI:10.1016/j.jhsg.2024.01.025

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引用次数: 0

摘要

使用自体移植物重建外周混合运动/感觉神经一直是金标准。神经异体移植研究的结果不一致且不符合生理学，包括成功和失败的运动神经再支配，因此目前神经异体移植的临床应用仅限于直径小于 3 厘米的非关键小直径感觉神经缺损。本范围综述旨在比较自体移植和异体移植神经重建混合运动/感觉神经的基础科学和临床应用结果。

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Nerve Autografts Versus Allografts for Mixed Motor/Sensory Nerve Reconstruction

Reconstruction of peripheral mixed motor/sensory nerves using autografts has remained the gold standard. Inconsistent and nonphysiologic results across nerve allograft studies, including successful and failed motor reinnervation, have limited the current clinical application of nerve allografts to noncritical small-diameter sensory nerve defects less than 3 cm. This scoping review aimed to compare outcomes in both basic science and clinical applications of autograft and allograft nerve reconstruction for mixed motor/sensory nerves.

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