动物模型在药物研发中的(误导性)作用

Thomas Hartung
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引用次数: 1

摘要

长期以来,小鼠和大鼠等动物一直被用于医学研究,以帮助了解疾病,并在人体试验前测试潜在的新疗法。然而,尽管动物研究取得了重要进展,但过度依赖动物模型也会误导药物开发。本文向普通读者解释了如何利用动物研究来开发新药、其益处和局限性,以及如何利用更准确、更人道的技术--动物试验的替代方法--来改进这一过程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The (misleading) role of animal models in drug development
Animals like mice and rats have long been used in medical research to help understand disease and test potential new treatments before human trials. However, while animal studies have contributed to important advances, too much reliance on animal models can also mislead drug development. This article explains for a general audience how animal research is used to develop new medicines, its benefits and limitations, and how more accurate and humane techniques—alternatives to animal testing—could improve this process.
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