尿酸在心血管疾病中的应用进展

IF 1.3 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Tian-ming Gan, Yu-yu Ye, Guan-lian Mo, Jin-yi Li
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引用次数: 0

摘要

由于高尿酸血症(HUA)在全球普遍存在,人们对尿酸(UA)的研究兴趣与日俱增。高尿酸血症是一种常见病,会带来各种不良后果,包括痛风和肾脏疾病。然而,最近的研究还发现尿酸与心血管疾病(CVD)的发生有关,如心房颤动(AF)和冠心病(CHD)。实验和临床研究广泛证明,血清尿酸水平升高对心血管健康有害。此外,血清尿酸水平已被确定为经皮冠状动脉介入治疗(PCI)和导管消融术后心血管疾病预后的预测因子。此外,降低尿酸水平疗法的使用对心血管疾病的治疗具有重要意义。本综述旨在整合目前有关血清尿酸与心血管疾病之间关系的证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Progress of uric acid in cardiovascular disease
Due to the global prevalence of hyperuricemia (HUA), there is growing interest in research on uric acid (UA). HUA is a common condition that has various adverse consequences, including gout and kidney disease. However, recent studies have also implicated UA in the development of cardiovascular diseases (CVD) such as atrial fibrillation (AF) and coronary heart disease (CHD). Experimental and clinical research has extensively demonstrated the detrimental effects of elevated serum UA levels on cardiovascular health. Furthermore, serum UA levels have been identified as predictors of CVD outcomes following percutaneous coronary intervention (PCI) and catheter ablation. Additionally, the use of UA-lowering therapy holds important implications for the management of CVD. This review aims to consolidate the current evidence on the relationship between serum UA and CVD.
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来源期刊
Cardiovascular Endocrinology & Metabolism
Cardiovascular Endocrinology & Metabolism CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
5.60
自引率
0.00%
发文量
24
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