金属基纳米抗氧化剂的分类及在医药和保健领域的应用

IF 2.6 4区材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY

Beilstein Journal of Nanotechnology Pub Date : 2024-04-12 DOI:10.3762/bjnano.15.36

N. N. Nam, Nguyen Khoi Song Tran, Tan Tai Nguyen, N. Trai, Nguyen Phuong Thuy, Hoang Dang Khoa Do, Nhu Hoa Thi Tran, K. Trinh

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引用次数: 0

摘要

抗氧化剂在预防氧化应激方面发挥着重要作用，已被广泛应用于医药和保健领域。然而，天然抗氧化剂存在稳定性低、难以长期储存、大规模生产成本高等局限性。随着纳米技术的长足进步，纳米材料因其稳定性高、易于储存、时效性强、成本低等优点，已成为改善天然抗氧化剂局限性的一种有前途的解决方案。在具有抗氧化活性的各类纳米材料中，金属基纳米抗氧化剂因其原子结构中存在一个未配对的电子而表现出卓越的反应活性。在本综述中，我们总结了一些新型金属基纳米抗氧化剂，并将其分为两大类，即断链型和预防型抗氧化纳米材料。此外，还讨论了抗氧化纳米材料在医药和保健领域的应用。这篇综述加深了人们对金属基纳米抗氧化剂机理的理解，并为在医药和保健领域使用这些纳米材料提供了指导。

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Classification and application of metal-based nanoantioxidants in medicine and healthcare

Antioxidants play an important role in the prevention of oxidative stress and have been widely used in medicine and healthcare. However, natural antioxidants have several limitations such as low stability, difficult long-term storage, and high cost of large-scale production. Along with significant advances in nanotechnology, nanomaterials have emerged as a promising solution to improve the limitations of natural antioxidants because of their high stability, easy storage, time effectiveness, and low cost. Among various types of nanomaterials exhibiting antioxidant activity, metal-based nanoantioxidants show excellent reactivity because of the presence of an unpaired electron in their atomic structure. In this review, we summarize some novel metal-based nanoantioxidants and classify them into two main categories, namely chain-breaking and preventive antioxidant nanomaterials. In addition, the applications of antioxidant nanomaterials in medicine and healthcare are also discussed. This review provides a deeper understanding of the mechanisms of metal-based nanoantioxidants and a guideline for using these nanomaterials in medicine and healthcare.

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来源期刊

Beilstein Journal of Nanotechnology NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY

CiteScore

5.70

自引率

3.20%

发文量

109

审稿时长

2 months

期刊介绍： The Beilstein Journal of Nanotechnology is an international, peer-reviewed, Open Access journal. It provides a unique platform for rapid publication without any charges (free for author and reader) – Platinum Open Access. The content is freely accessible 365 days a year to any user worldwide. Articles are available online immediately upon publication and are publicly archived in all major repositories. In addition, it provides a platform for publishing thematic issues (theme-based collections of articles) on topical issues in nanoscience and nanotechnology. The journal is published and completely funded by the Beilstein-Institut, a non-profit foundation located in Frankfurt am Main, Germany. The editor-in-chief is Professor Thomas Schimmel – Karlsruhe Institute of Technology. He is supported by more than 20 associate editors who are responsible for a particular subject area within the scope of the journal.