Shambhavi, Puja Priyadarshni, N. Kumari, Ratnesh Kumar
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Advances in Electrochemical Sensing of Depression Biomarker Serotonin: A Comprehensive Review
The present review deals with detection of serotonin (5-HT) by electrochemical techniques using various modified electrodes. Serotonin is an important monoamine neurotransmitter, psychoactive agent, and bioactive component. Its detection has a very significant contribution in diagnosing and treating many neurological diseases. Electrochemical techniques provide simple, fast, high selective, sensitive, reproducible, and the low-cost method for the determination of 5-HT. We have extensively reviewed the recently developed approaches in which serotonin has been sensitively detected using modified electrodes even in the presence of interfering agents. The analytical characteristics such as linear range and detection limit on various modified electrode have been compared in the review.
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