加热烟草制品:减少危害、改善室内空气质量的潜力和进一步研究的必要性

SciEnggJ Pub Date : 2024-04-15 DOI:10.54645/2024171pwy-56
Aldwin Camance
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引用次数: 0

摘要

空气污染是菲律宾的一个主要问题,室内和室外空气污染是造成菲律宾人死亡的最主要原因。然而,最新的法规只涉及室外环境空气污染。室内空气污染很少受到监测或研究。即使菲律宾人 80% 以上的时间都在室内度过,但大多数政府官方监测数据也只涉及室外空气污染。室内吸烟可能是造成室内空气污染物超标的一个原因。据报道,菲律宾新推出的加热烟草产品可减少使用者暴露于空气污染物的危害。我们通过查阅有关加热烟草制品使用及其影响的 282 项研究、研究论文、书籍和叙述,对此进行了调查。这些研究表明,与烟草烟雾相比,使用 HTP 可减少气溶胶中有害和潜在有害化合物(HPHC)的释放,降低室内环境中 HPHC 的浓度。短期临床前研究也表明,潜在接触这些高有害物质的生物标志物有所减少,风险计算显示,不同人群的癌症发病率也有所降低。虽然仍需要进行长期的流行病学研究,才能最终确定使用 HTP 可能带来的风险,但初步研究结果已经取得广泛共识,即从吸烟完全转为使用 HTP 带来的危害风险较小。不过,审查结果表明,关于 HTP 如何影响菲律宾等热带国家的室内空气质量,还有许多问题需要研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Heated tobacco products: Potentials of harm reduction, improvement of indoor air quality and the need for further studies
Air pollution is a major concern in the Philippines, with indoor and outdoor air pollution among the highest causes of mortality in the country. However, the latest regulations deal only with ambient outdoor air pollution. Indoor air pollution is seldom monitored or studied. Most of the official government monitoring data also deal with outdoor air pollution even if Filipinos spend more than 80% of their time indoors. Smoking indoors can be a cause of excess air pollutants in the indoor setting. Heated Tobacco products, newly introduced in the country, have been reported to reduce the harm of exposure to users to air pollutants. We investigated this through the review of 282 studies, research papers, books, and narratives about HTP use and their effects. These studies show reduced release of harmful and potentially harmful compounds (HPHC) in the aerosol and lower concentrations of HPHCs in the indoor environment when using HTPs as compared to tobacco smoke. Short term pre-clinical studies also show a reduction in the biomarkers for potential exposure to these HPHCs and risk calculations have shown a reduction in cancer potencies across populations. While long-term epidemiological studies are still required to determine with finality the risks that HTP use may have, there is already wide agreement in the initial results that the complete switch to HTP use from cigarette smoking presents less risks of harm. The review, however, shows that much has to be studied about the manner by which HTPs can affect indoor air quality in tropical countries such as the Philippines.
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