希腊非孕妇生殖器支原体的抗菌药耐药性：过去 15 年的趋势。

IF 2.5 4区生物学 Q3 MICROBIOLOGY

Future microbiology Pub Date : 2024-04-17 DOI:10.2217/fmb-2023-0238

V. Koumaki, A. Chasiakou, M. Kantzanou, A. Tsakris, S. Baka

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引用次数: 0

摘要

目的：研究从育龄非孕妇宫颈内膜样本（n = 8 336）中提取的生殖器支原体的抗菌药敏感性。材料与方法使用支原体 IST2 试剂盒进行分离和药敏试验。结果多达 2093 份样本支原体检测呈阳性。绝大多数（>96%）解脲支原体仍然对四环素、强力霉素、交沙霉素和普利霉素敏感，而对阿奇霉素和氟喹诺酮类药物的敏感率则明显下降。人型支原体对多西环素、普里什霉素和交沙霉素的敏感率较高（98.1%-100%），而对四环素和氟喹诺酮类药物的敏感率则低得多。结论多西环素对支原体的治疗效果仍然很强，但对其他抗菌药物的敏感性却明显降低。

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Antimicrobial resistance of genital mycoplasmas recovered from nonpregnant women in Greece: trends over the last 15 years.

Aim: To study antimicrobial susceptibilities of genital mycoplasmas recovered from endocervical samples of reproductive-age, nonpregnant women (n = 8,336). Materials & methods: For isolation and susceptibility testing, the Mycoplasma IST2 kit was used. Results: As many as 2093 samples were positive for mycoplasmas. The vast majority (>96%) of Ureaplasma urealyticum remained susceptible to tetracycline, doxycycline, josamycin and pristinamycin, whereas susceptibility rates to azithromycin and fluoroquinolones were significantly decreased. Mycoplasma hominis exhibited high susceptibility rates to doxycycline, pristinamycin and josamycin (98.1-100%), while susceptibilities to tetracycline and fluoroquinolones were considerably lower. Conclusion: Doxycycline remained highly potent for treating mycoplasmas; nevertheless, susceptibilities to other antimicrobials were significantly diminished.

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来源期刊

Future microbiology 生物-微生物学

CiteScore

4.90

自引率

3.20%

发文量

134

审稿时长

6-12 weeks

期刊介绍： Future Microbiology delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for this increasingly important and vast area of research.