MINFLUX 纳米技术：纳米级生物物质可视化

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-04-25 DOI:10.1111/jmi.13306

Alexander Carsten, A. Failla, Martin Aepfelbacher

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引用次数: 0

摘要

自 2017 年推出以来，MINFLUX 纳米透视技术已经证明，它能够以几纳米的超高定位精度观察荧光分子。在本综述中，我们将简要介绍与 MINFLUX 成像和跟踪相关的技术实现、荧光标记开发和生物研究。我们还就 MINFLUX 纳米技术及其衍生技术在未来如何影响生物成像提出了一些想法。这一见解旨在为希望简要了解 MINFLUX 纳米透镜从理论到应用的读者提供一个总体出发点。

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MINFLUX nanoscopy: Visualising biological matter at the nanoscale level

Since its introduction in 2017, MINFLUX nanoscopy has shown that it can visualise fluorescent molecules with an exceptional localisation precision of a few nanometres. In this overview, we provide a brief insight into technical implementations, fluorescent marker developments and biological studies that have been conducted in connection with MINFLUX imaging and tracking. We also formulate ideas on how MINFLUX nanoscopy and derived technologies could influence bioimaging in the future. This insight is intended as a general starting point for an audience looking for a brief overview of MINFLUX nanoscopy from theory to application.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.