{"title":"药物基因组学指导治疗略微提高了抗抑郁疗效","authors":"","doi":"10.1002/pu.31165","DOIUrl":null,"url":null,"abstract":"<p>A systematic review and meta-analysis encompassing 15 clinical trials has concluded that pharmacogenomic-guided depression treatment results in a small improvement in antidepressant efficacy relative to treatment as usual. There was no difference in treatment discontinuation rates between pharmacogenomic-guided and conventional treatment.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pharmacogenomic-guided treatment slightly improves antidepressant efficacy\",\"authors\":\"\",\"doi\":\"10.1002/pu.31165\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>A systematic review and meta-analysis encompassing 15 clinical trials has concluded that pharmacogenomic-guided depression treatment results in a small improvement in antidepressant efficacy relative to treatment as usual. There was no difference in treatment discontinuation rates between pharmacogenomic-guided and conventional treatment.</p>\",\"PeriodicalId\":22275,\"journal\":{\"name\":\"The Brown University Psychopharmacology Update\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-04-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Brown University Psychopharmacology Update\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/pu.31165\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Brown University Psychopharmacology Update","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/pu.31165","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A systematic review and meta-analysis encompassing 15 clinical trials has concluded that pharmacogenomic-guided depression treatment results in a small improvement in antidepressant efficacy relative to treatment as usual. There was no difference in treatment discontinuation rates between pharmacogenomic-guided and conventional treatment.