协作克罗斯小鼠偶氮甲烷诱发结直肠肿瘤易感性的遗传和微生物决定因素及其对人类癌症的影响

IF 12.2 1区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY
Dan Li, Chenhan Zhong, Mengyuan Yang, Li He, Hang Chang, Ning Zhu, Susan E Celniker, David W Threadgill, Antoine M Snijders, Jian-Hua Mao, Ying Yuan
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引用次数: 0

摘要

宿主遗传学和肠道微生物组(GM)在结直肠肿瘤易感性(CTS)中的相互作用仍然缺乏深入研究。我们利用协作交叉小鼠群体模型来确定...
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Genetic and microbial determinants of azoxymethane-induced colorectal tumor susceptibility in Collaborative Cross mice and their implication in human cancer
The insights into interactions between host genetics and gut microbiome (GM) in colorectal tumor susceptibility (CTS) remains lacking. We used Collaborative Cross mouse population model to identify...
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来源期刊
Gut Microbes
Gut Microbes Medicine-Microbiology (medical)
CiteScore
18.20
自引率
3.30%
发文量
196
审稿时长
10 weeks
期刊介绍: The intestinal microbiota plays a crucial role in human physiology, influencing various aspects of health and disease such as nutrition, obesity, brain function, allergic responses, immunity, inflammatory bowel disease, irritable bowel syndrome, cancer development, cardiac disease, liver disease, and more. Gut Microbes serves as a platform for showcasing and discussing state-of-the-art research related to the microorganisms present in the intestine. The journal emphasizes mechanistic and cause-and-effect studies. Additionally, it has a counterpart, Gut Microbes Reports, which places a greater focus on emerging topics and comparative and incremental studies.
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