膀胱内吉西他滨和多西他赛治疗卡介苗-桂林杆菌无效的非肌层浸润性膀胱尿路上皮癌的 II 期试验。

Sunil H Patel, Andrew T Gabrielson, Sin Chan, Deborah Schwartz, Connie Collins, Nirmish Singla, Bruce Trock, Trinity J Bivalacqua, Noah Hahn, Max R Kates
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引用次数: 0

摘要

膀胱内吉西他滨和多西他赛(GemDoce)联合疗法作为卡介苗(BCG)无反应性非肌层浸润性膀胱尿路上皮癌(NMIBC)患者的二线疗法已被证明具有疗效。在卡介苗普遍短缺的情况下,我们进行了一项 2 期前瞻性试验,以评估 GemDoce 对卡介苗无效的 NMIBC 的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Phase II Trial of Intravesical Gemcitabine and Docetaxel in the Treatment of Bacillus Calmette-Guérin‒Naïve Nonmuscle-Invasive Urothelial Carcinoma of the Bladder.
Combination intravesical gemcitabine and docetaxel (GemDoce) has demonstrated efficacy as second-line therapy for patients with bacillus Calmette-Guérin (BCG)‒unresponsive nonmuscle-invasive urothelial carcinoma of the bladder (NMIBC). In the context of widespread BCG shortages, we performed a phase 2 prospective trial to assess GemDoce for BCG-naïve NMIBC.
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