接受激素治疗的不同性别和变性患者胰腺炎发病率增加：一项病例系列研究

IF 3.3 Q2 GASTROENTEROLOGY & HEPATOLOGY

BMJ Open Gastroenterology Pub Date : 2024-04-01 DOI:10.1136/bmjgast-2023-001312

Alexander Podboy, Catherine Casey, Ross C D Buerlein, Daniel S Strand, Vanessa M Shami, Andrew Y Wang

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引用次数: 0

摘要

背景有关性别不符（GNC）人群胃肠道特异性病变发病率的数据十分有限。方法对接受和未接受性别确认激素疗法（GAHT）的变性人和 GNC 患者的胰腺炎发病率进行回顾性分析。结果在接受激素治疗的 1333 名患者中，有 7 人发生了胰腺炎。在 615 名没有使用过 GAHT 的患者中，0 人患胰腺炎。接受过 GAHT 治疗的患者胰腺炎发病率为 6.96（95% CI 2.76 至 848.78）。结论临床医生在治疗 GNC 患者时应注意这种可能的关联。

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Increased rate of pancreatitis in gender diverse and transgender patients on hormone therapy: a case series study

Background There is limited data on the incidence of gastrointestinal-specific pathology in gender non-conforming (GNC) populations. Methods Retrospective analysis of pancreatitis incidence rates in transgender and GNC persons exposed and not exposed to gender-affirming hormone therapy (GAHT). Results 7 of the 1333 patients on hormone therapy had an incidence of pancreatitis. 0 of the 615 patients with no history of GAHT use developed pancreatitis. Representing a 6.96 (95% CI 2.76 to 848.78) for the development of pancreatitis in patients with exposure to GAHT therapy. Conclusion Clinicians working with GNC individuals should be aware of this possible association Data are available upon reasonable request.

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来源期刊

BMJ Open Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

5.90

自引率

3.20%

发文量

审稿时长

2 weeks

期刊介绍： BMJ Open Gastroenterology is an online-only, peer-reviewed, open access gastroenterology journal, dedicated to publishing high-quality medical research from all disciplines and therapeutic areas of gastroenterology. It is the open access companion journal of Gut and is co-owned by the British Society of Gastroenterology. The journal publishes all research study types, from study protocols to phase I trials to meta-analyses, including small or specialist studies. Publishing procedures are built around continuous publication, publishing research online as soon as the article is ready.