预测人类 MDC1 基因的有害非同义 SNPs：一种硅学方法

IF 2.1 4区医学 Q3 ANDROLOGY

Systems Biology in Reproductive Medicine Pub Date : 2024-04-17 DOI:10.1080/19396368.2024.2325699

Vaishnavee Thote, Susha Dinesh, Sameer Sharma

引用次数: 0

摘要

MDC1（DNA损伤检查点介导蛋白1）的功能是促进众多DNA损伤应答（DDR）成分定位到DNA双链断裂位点。MDC1是DNA损伤检查点蛋白1的一个不可或缺的协同...

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Prediction of deleterious non-synonymous SNPs of human MDC1 gene: an in silico approach

MDC1 (Mediator of DNA damage Checkpoint protein 1) functions to facilitate the localization of numerous DNA damage response (DDR) components to DNA double-strand break sites. MDC1 is an integral co...

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来源期刊

Systems Biology in Reproductive Medicine 医学-男科学

CiteScore

4.30

自引率

4.20%

发文量

审稿时长

>12 weeks

期刊介绍： Systems Biology in Reproductive Medicine, SBiRM, publishes Research Articles, Communications, Applications Notes that include protocols a Clinical Corner that includes case reports, Review Articles and Hypotheses and Letters to the Editor on human and animal reproduction. The journal will highlight the use of systems approaches including genomic, cellular, proteomic, metabolomic, bioinformatic, molecular, and biochemical, to address fundamental questions in reproductive biology, reproductive medicine, and translational research. The journal publishes research involving human and animal gametes, stem cells, developmental biology and toxicology, and clinical care in reproductive medicine. Specific areas of interest to the journal include: male factor infertility and germ cell biology, reproductive technologies (gamete micro-manipulation and cryopreservation, in vitro fertilization/embryo transfer (IVF/ET) and contraception. Research that is directed towards developing new or enhanced technologies for clinical medicine or scientific research in reproduction is of significant interest to the journal.