通过因果推理和中介分析，解读体育锻炼、炎症性肠病和肥胖症/BMl 之间复杂的相互作用

medRxiv - Gastroenterology Pub Date : 2024-04-15 DOI:10.1101/2024.04.15.24305823

Minjing Chang, Yuhui Zhao, Jun Qiao, Hongxia Li, Linlin Jia, Kaixin Yao, Nan Li, Peifeng He

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引用次数: 0

摘要

背景和目的有关体力活动（PA）与炎症性肠病（IBD）（包括克罗恩病（CD）和溃疡性结肠炎（UC））之间关系的观察性研究报告的结果并不一致。此外，PA 与 IBD 之间的潜在中介因素仍然未知。我们的目的是研究 PA 对 IBD 的因果效应以及 BMI 在 PA 和 IBD 之间的中介作用。

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Deciphering the complex interplay between physical activity, inflammatory bowel disease and obesity/BMl through causal inference and mediation analyses

Background and Aims Observational studies on the association between physical activity (PA) and inflammatory bowel diseases (IBDs), including Crohn’s disease (CD) and ulcerative colitis (UC), report inconsistent results. Moreover, the underlying mediator between PA and IBDs remains unknown. We aimed to investigate the causal effect of PA on IBD and the role of BMI as a mediator between PA and IBD.

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medRxiv - Gastroenterology

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