儿科人群阿片类药物使用障碍：围术期疼痛管理和精确阿片类药物镇痛的注意事项

IF 3.6 3区医学 Q2 PHARMACOLOGY & PHARMACY

Expert Review of Clinical Pharmacology Pub Date : 2024-04-16 DOI:10.1080/17512433.2024.2343915

Yun Han Chen, Anastasios Xenitidis, Paul Hoffman, Leslie Matthews, Swathi G. Padmanabhan, Lakshmi Aravindan, Ruth Ressler, Inesh Sivam, Sahana Sivam, Chase F. Gillispie, Senthilkumar Sadhasivam

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引用次数: 0

摘要

阿片类药物通常用于围手术期镇痛，但儿童术后严重疼痛和阿片类药物相关不良反应的发生率仍然很高。持续和严重的急性手术疼痛是导致儿童死亡的主要原因。

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Opioid use disorder in pediatric populations: considerations for perioperative pain management and precision opioid analgesia

Opioids are commonly used for perioperative analgesia, yet children still suffer high rates of severe post-surgical pain and opioid-related adverse effects. Persistent and severe acute surgical pai...

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来源期刊

Expert Review of Clinical Pharmacology PHARMACOLOGY & PHARMACY-

CiteScore

7.30

自引率

2.30%

发文量

127

期刊介绍： Advances in drug development technologies are yielding innovative new therapies, from potentially lifesaving medicines to lifestyle products. In recent years, however, the cost of developing new drugs has soared, and concerns over drug resistance and pharmacoeconomics have come to the fore. Adverse reactions experienced at the clinical trial level serve as a constant reminder of the importance of rigorous safety and toxicity testing. Furthermore the advent of pharmacogenomics and ‘individualized’ approaches to therapy will demand a fresh approach to drug evaluation and healthcare delivery. Clinical Pharmacology provides an essential role in integrating the expertise of all of the specialists and players who are active in meeting such challenges in modern biomedical practice.