丙烷-2-磺酸十八-9-烯基酰胺是一种新型 PPARα/γ 双激动剂，可减轻 AD 小鼠学习记忆的分子病理改变

IF 1.7 4区医学 Q3 CLINICAL NEUROLOGY

Neurological Research Pub Date : 2024-04-05 DOI:10.1080/01616412.2024.2325313

Ying Li, Yanan Zhang, Qing Wang, Chuang Wu, Guicheng Du, Ying Zeng, Zhengmao Song, Xing Jiang, Xun Jiang, Rengong Zhuo, Jingwen Li

引用次数: 0

摘要

以往的研究表明，丙烷-2-磺酸十八-9-烯基酰胺（N15）在缺血性中风后的炎症反应和神经元损伤中发挥着保护作用。然而，...

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Propane-2-sulfonic acid octadec-9-enyl-amide, a novel PPARα/γ dual agonist, attenuates molecular pathological alterations in learning memory in AD mice

Previous studies have revealed that Propane-2-sulfonic acid octadec-9-enyl-amide(N15) exerts a protective role in the inflammatory response after ischemic stroke and in neuronal damage. However, li...

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来源期刊

Neurological Research 医学-临床神经学

CiteScore

3.60

自引率

0.00%

发文量

116

审稿时长

5.3 months

期刊介绍： Neurological Research is an international, peer-reviewed journal for reporting both basic and clinical research in the fields of neurosurgery, neurology, neuroengineering and neurosciences. It provides a medium for those who recognize the wider implications of their work and who wish to be informed of the relevant experience of others in related and more distant fields. The scope of the journal includes: •Stem cell applications •Molecular neuroscience •Neuropharmacology •Neuroradiology •Neurochemistry •Biomathematical models •Endovascular neurosurgery •Innovation in neurosurgery.