{"title":"聚维酮碘在减少手术部位感染中的作用","authors":"A. Haleem, C. L. Abad","doi":"10.1007/s11908-024-00841-z","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose of Review</h3><p>Surgical site infections (SSIs) are associated with significant morbidity and mortality. Given the role of endogenous carriage of <i>Staphylococcus aureus</i>, current patient decolonization strategies revolve around the application of topical antiseptic agents prior to and at the time of surgery.</p><h3 data-test=\"abstract-sub-heading\">Recent Findings</h3><p>Intranasal single-application povidone-iodine (PVP-I) on the day of surgery is an emerging, attractive alternative to the established approach of a 5-day course of intranasal mupirocin for preoperative decolonization.</p><h3 data-test=\"abstract-sub-heading\">Summary</h3><p>PVP-I appears more convenient and cost-effective for both patients and healthcare systems, and its role in reducing SSI is under investigation. However, most published literature consists of retrospective, single-center studies primarily done in orthopedic surgical populations. Based on current data, PVP-I appears to be as equally effective in SSI reduction as mupirocin, but larger and better-quality studies are needed to implement a change from currently established preoperative decontamination practices.</p>","PeriodicalId":48839,"journal":{"name":"Current Infectious Disease Reports","volume":null,"pages":null},"PeriodicalIF":3.1000,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Role of Povidone-Iodine in Reducing Surgical Site Infection\",\"authors\":\"A. Haleem, C. L. Abad\",\"doi\":\"10.1007/s11908-024-00841-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<h3 data-test=\\\"abstract-sub-heading\\\">Purpose of Review</h3><p>Surgical site infections (SSIs) are associated with significant morbidity and mortality. Given the role of endogenous carriage of <i>Staphylococcus aureus</i>, current patient decolonization strategies revolve around the application of topical antiseptic agents prior to and at the time of surgery.</p><h3 data-test=\\\"abstract-sub-heading\\\">Recent Findings</h3><p>Intranasal single-application povidone-iodine (PVP-I) on the day of surgery is an emerging, attractive alternative to the established approach of a 5-day course of intranasal mupirocin for preoperative decolonization.</p><h3 data-test=\\\"abstract-sub-heading\\\">Summary</h3><p>PVP-I appears more convenient and cost-effective for both patients and healthcare systems, and its role in reducing SSI is under investigation. However, most published literature consists of retrospective, single-center studies primarily done in orthopedic surgical populations. Based on current data, PVP-I appears to be as equally effective in SSI reduction as mupirocin, but larger and better-quality studies are needed to implement a change from currently established preoperative decontamination practices.</p>\",\"PeriodicalId\":48839,\"journal\":{\"name\":\"Current Infectious Disease Reports\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2024-04-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Infectious Disease Reports\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s11908-024-00841-z\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Infectious Disease Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11908-024-00841-z","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Role of Povidone-Iodine in Reducing Surgical Site Infection
Purpose of Review
Surgical site infections (SSIs) are associated with significant morbidity and mortality. Given the role of endogenous carriage of Staphylococcus aureus, current patient decolonization strategies revolve around the application of topical antiseptic agents prior to and at the time of surgery.
Recent Findings
Intranasal single-application povidone-iodine (PVP-I) on the day of surgery is an emerging, attractive alternative to the established approach of a 5-day course of intranasal mupirocin for preoperative decolonization.
Summary
PVP-I appears more convenient and cost-effective for both patients and healthcare systems, and its role in reducing SSI is under investigation. However, most published literature consists of retrospective, single-center studies primarily done in orthopedic surgical populations. Based on current data, PVP-I appears to be as equally effective in SSI reduction as mupirocin, but larger and better-quality studies are needed to implement a change from currently established preoperative decontamination practices.
期刊介绍：
This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of infectious disease.
We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as HIV/AIDS, sexually transmitted diseases, tropical and travel medicine, and urinary tract infections. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists.
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