{"title":"用于细菌感染性皮肤伤口愈合的光热抗菌平台的制造：综述","authors":"Mei Han, Wenjing Sun, Yi Chen and Hongbin Li","doi":"10.1039/D4ME00010B","DOIUrl":null,"url":null,"abstract":"<p >Antibiotics are currently the main strategy to treat bacterial infections, but they can cause antimicrobial resistance. Thus, it is urgent to solve this problem. The emergence of photothermal therapy provides a new opportunity for the prevention and control of bacterial infection. In recent years, photothermal agents have been widely used in infection control and wound healing due to their strong antibacterial properties and low drug resistance. Photothermal agents (PTAs) are nanomaterials themselves, or small molecules loaded in nanoparticles, and are the basic elements of PPT. In this review, we discuss the characteristics of wound dressings in skin wound healing, types and main functions of antibacterial photothermal therapy (PTA), and the fabrication and application of wound dressings. Finally, the current challenges and future development of PTAs as a photothermal antibacterial platform for wound healing are summarized and discussed.</p>","PeriodicalId":91,"journal":{"name":"Molecular Systems Design & Engineering","volume":" 8","pages":" 800-813"},"PeriodicalIF":3.2000,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Fabrication of a photothermal antibacterial platform for bacterial infectious skin wound healing: a review\",\"authors\":\"Mei Han, Wenjing Sun, Yi Chen and Hongbin Li\",\"doi\":\"10.1039/D4ME00010B\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >Antibiotics are currently the main strategy to treat bacterial infections, but they can cause antimicrobial resistance. Thus, it is urgent to solve this problem. The emergence of photothermal therapy provides a new opportunity for the prevention and control of bacterial infection. In recent years, photothermal agents have been widely used in infection control and wound healing due to their strong antibacterial properties and low drug resistance. Photothermal agents (PTAs) are nanomaterials themselves, or small molecules loaded in nanoparticles, and are the basic elements of PPT. In this review, we discuss the characteristics of wound dressings in skin wound healing, types and main functions of antibacterial photothermal therapy (PTA), and the fabrication and application of wound dressings. Finally, the current challenges and future development of PTAs as a photothermal antibacterial platform for wound healing are summarized and discussed.</p>\",\"PeriodicalId\":91,\"journal\":{\"name\":\"Molecular Systems Design & Engineering\",\"volume\":\" 8\",\"pages\":\" 800-813\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2024-04-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Molecular Systems Design & Engineering\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://pubs.rsc.org/en/content/articlelanding/2024/me/d4me00010b\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, PHYSICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular Systems Design & Engineering","FirstCategoryId":"5","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2024/me/d4me00010b","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
摘要
抗生素是目前治疗细菌感染的主要策略，但抗生素会导致细菌产生耐药性，解决这一问题迫在眉睫。光热疗法的出现为预防和控制细菌感染提供了新的契机。制备用于细菌感染伤口的光热抗菌平台非常重要。近年来，光热制剂因其抗菌性强、耐药性低等特点被广泛应用于感染控制和伤口愈合领域。PTAs 本身是纳米材料，或纳米颗粒中装载的小分子，是 PTT 的基本要素。在这篇综述中，我们讨论了皮肤伤口愈合中伤口敷料的特点、抗菌光热疗法（PTA）的类型和主要功能、伤口敷料的制造和应用。最后，总结并讨论了作为伤口愈合光热抗菌平台的 PTA 目前面临的挑战和未来的发展。
Fabrication of a photothermal antibacterial platform for bacterial infectious skin wound healing: a review
Antibiotics are currently the main strategy to treat bacterial infections, but they can cause antimicrobial resistance. Thus, it is urgent to solve this problem. The emergence of photothermal therapy provides a new opportunity for the prevention and control of bacterial infection. In recent years, photothermal agents have been widely used in infection control and wound healing due to their strong antibacterial properties and low drug resistance. Photothermal agents (PTAs) are nanomaterials themselves, or small molecules loaded in nanoparticles, and are the basic elements of PPT. In this review, we discuss the characteristics of wound dressings in skin wound healing, types and main functions of antibacterial photothermal therapy (PTA), and the fabrication and application of wound dressings. Finally, the current challenges and future development of PTAs as a photothermal antibacterial platform for wound healing are summarized and discussed.
期刊介绍：
Molecular Systems Design & Engineering provides a hub for cutting-edge research into how understanding of molecular properties, behaviour and interactions can be used to design and assemble better materials, systems, and processes to achieve specific functions. These may have applications of technological significance and help address global challenges.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
