2024 年的成人脑肿瘤研究:现状、挑战和建议

IF 4 2区 医学 Q1 CLINICAL NEUROLOGY
Karin Purshouse, Helen J. Bulbeck, Alasdair G. Rooney, Karen E. Noble, Ross D. Carruthers, Gerard Thompson, Petra Hamerlik, Christina Yap, Kathreena M. Kurian, Sarah J. Jefferies, Juanita S. Lopez, Michael D. Jenkinson, C. Oliver Hanemann, Lucy F. Stead
{"title":"2024 年的成人脑肿瘤研究:现状、挑战和建议","authors":"Karin Purshouse, Helen J. Bulbeck, Alasdair G. Rooney, Karen E. Noble, Ross D. Carruthers, Gerard Thompson, Petra Hamerlik, Christina Yap, Kathreena M. Kurian, Sarah J. Jefferies, Juanita S. Lopez, Michael D. Jenkinson, C. Oliver Hanemann, Lucy F. Stead","doi":"10.1111/nan.12979","DOIUrl":null,"url":null,"abstract":"In 2015, a groundswell of brain tumour patient, carer and charity activism compelled the UK Minister for Life Sciences to form a brain tumour research task and finish group. This resulted, in 2018, with the UK government pledging £20m of funding, to be paralleled with £25m from Cancer Research UK, specifically for neuro‐oncology research over the subsequent 5 years. Herein, we review if and how the adult brain tumour research landscape in the United Kingdom has changed over that time and what challenges and bottlenecks remain. We have identified seven universal brain tumour research priorities and three cross‐cutting themes, which span the research spectrum from bench to bedside and back again. We discuss the status, challenges and recommendations for each one, specific to the United Kingdom.","PeriodicalId":19151,"journal":{"name":"Neuropathology and Applied Neurobiology","volume":"43 1","pages":""},"PeriodicalIF":4.0000,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Adult brain tumour research in 2024: Status, challenges and recommendations\",\"authors\":\"Karin Purshouse, Helen J. Bulbeck, Alasdair G. Rooney, Karen E. Noble, Ross D. Carruthers, Gerard Thompson, Petra Hamerlik, Christina Yap, Kathreena M. Kurian, Sarah J. Jefferies, Juanita S. Lopez, Michael D. Jenkinson, C. Oliver Hanemann, Lucy F. Stead\",\"doi\":\"10.1111/nan.12979\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In 2015, a groundswell of brain tumour patient, carer and charity activism compelled the UK Minister for Life Sciences to form a brain tumour research task and finish group. This resulted, in 2018, with the UK government pledging £20m of funding, to be paralleled with £25m from Cancer Research UK, specifically for neuro‐oncology research over the subsequent 5 years. Herein, we review if and how the adult brain tumour research landscape in the United Kingdom has changed over that time and what challenges and bottlenecks remain. We have identified seven universal brain tumour research priorities and three cross‐cutting themes, which span the research spectrum from bench to bedside and back again. We discuss the status, challenges and recommendations for each one, specific to the United Kingdom.\",\"PeriodicalId\":19151,\"journal\":{\"name\":\"Neuropathology and Applied Neurobiology\",\"volume\":\"43 1\",\"pages\":\"\"},\"PeriodicalIF\":4.0000,\"publicationDate\":\"2024-04-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neuropathology and Applied Neurobiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/nan.12979\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuropathology and Applied Neurobiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/nan.12979","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0

摘要

2015 年,脑肿瘤患者、护理者和慈善机构的积极行动迫使英国生命科学部长成立了一个脑肿瘤研究工作组。其结果是,2018 年,英国政府承诺提供 2000 万英镑的资金,英国癌症研究中心(Cancer Research UK)也将提供 2500 万英镑的资金,专门用于随后 5 年的神经肿瘤学研究。在此,我们回顾了英国成人脑肿瘤研究的格局在这段时间内是否发生了变化,以及发生了怎样的变化,还存在哪些挑战和瓶颈。我们确定了七项通用脑肿瘤研究优先事项和三个横向主题,这些优先事项和主题涵盖了从实验室到临床再到临床的所有研究领域。我们针对英国的具体情况,讨论了每项研究的现状、挑战和建议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Adult brain tumour research in 2024: Status, challenges and recommendations

Adult brain tumour research in 2024: Status, challenges and recommendations
In 2015, a groundswell of brain tumour patient, carer and charity activism compelled the UK Minister for Life Sciences to form a brain tumour research task and finish group. This resulted, in 2018, with the UK government pledging £20m of funding, to be paralleled with £25m from Cancer Research UK, specifically for neuro‐oncology research over the subsequent 5 years. Herein, we review if and how the adult brain tumour research landscape in the United Kingdom has changed over that time and what challenges and bottlenecks remain. We have identified seven universal brain tumour research priorities and three cross‐cutting themes, which span the research spectrum from bench to bedside and back again. We discuss the status, challenges and recommendations for each one, specific to the United Kingdom.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
8.20
自引率
2.00%
发文量
87
审稿时长
6-12 weeks
期刊介绍: Neuropathology and Applied Neurobiology is an international journal for the publication of original papers, both clinical and experimental, on problems and pathological processes in neuropathology and muscle disease. Established in 1974, this reputable and well respected journal is an international journal sponsored by the British Neuropathological Society, one of the world leading societies for Neuropathology, pioneering research and scientific endeavour with a global membership base. Additionally members of the British Neuropathological Society get 50% off the cost of print colour on acceptance of their article.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信