{"title":"检测内源性激素及其对辅助医疗的影响","authors":"Jiayu Yu , Qilin Wang , Yinchao Chen , Yizhen Ouyang , Haitao Xu","doi":"10.1016/j.biosx.2024.100477","DOIUrl":null,"url":null,"abstract":"<div><p>The detection of endogenous hormones is of great significance for disease diagnosis, treatment guidance, and the development of personalized healthcare. By using biosensors, real-time monitoring and quantitative analysis of endogenous hormone levels can be achieved, providing scientific basis for clinical decision-making. The continuous innovation in this field will bring new breakthroughs in medical diagnosis and treatment, which are expected to accelerate the early detection of diseases and the implementation of personalized treatment plans. In this review, we mainly review the research progress of endogenous hormone biosensors based on different biological recognition elements, namely enzyme-based biosensors, immunobiosensors, aptamer-based biosensors, and molecularly imprinted polymer (MIP) based biosensors. Meanwhile, this paper also analyzes the detection efficiency and clinical application of these biosensors. Finally, we summarize the current challenges and future development directions of the different types of biosensors involved in the discussion.</p></div>","PeriodicalId":260,"journal":{"name":"Biosensors and Bioelectronics: X","volume":"18 ","pages":"Article 100477"},"PeriodicalIF":10.6100,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590137024000414/pdfft?md5=f277f569a5ac4ddc92ee8c86360f4fbc&pid=1-s2.0-S2590137024000414-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Detection of endogenous hormones and its effect on auxiliary medical treatment\",\"authors\":\"Jiayu Yu , Qilin Wang , Yinchao Chen , Yizhen Ouyang , Haitao Xu\",\"doi\":\"10.1016/j.biosx.2024.100477\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The detection of endogenous hormones is of great significance for disease diagnosis, treatment guidance, and the development of personalized healthcare. By using biosensors, real-time monitoring and quantitative analysis of endogenous hormone levels can be achieved, providing scientific basis for clinical decision-making. The continuous innovation in this field will bring new breakthroughs in medical diagnosis and treatment, which are expected to accelerate the early detection of diseases and the implementation of personalized treatment plans. In this review, we mainly review the research progress of endogenous hormone biosensors based on different biological recognition elements, namely enzyme-based biosensors, immunobiosensors, aptamer-based biosensors, and molecularly imprinted polymer (MIP) based biosensors. Meanwhile, this paper also analyzes the detection efficiency and clinical application of these biosensors. Finally, we summarize the current challenges and future development directions of the different types of biosensors involved in the discussion.</p></div>\",\"PeriodicalId\":260,\"journal\":{\"name\":\"Biosensors and Bioelectronics: X\",\"volume\":\"18 \",\"pages\":\"Article 100477\"},\"PeriodicalIF\":10.6100,\"publicationDate\":\"2024-04-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2590137024000414/pdfft?md5=f277f569a5ac4ddc92ee8c86360f4fbc&pid=1-s2.0-S2590137024000414-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biosensors and Bioelectronics: X\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2590137024000414\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Biochemistry, Genetics and Molecular Biology\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biosensors and Bioelectronics: X","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2590137024000414","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
Detection of endogenous hormones and its effect on auxiliary medical treatment
The detection of endogenous hormones is of great significance for disease diagnosis, treatment guidance, and the development of personalized healthcare. By using biosensors, real-time monitoring and quantitative analysis of endogenous hormone levels can be achieved, providing scientific basis for clinical decision-making. The continuous innovation in this field will bring new breakthroughs in medical diagnosis and treatment, which are expected to accelerate the early detection of diseases and the implementation of personalized treatment plans. In this review, we mainly review the research progress of endogenous hormone biosensors based on different biological recognition elements, namely enzyme-based biosensors, immunobiosensors, aptamer-based biosensors, and molecularly imprinted polymer (MIP) based biosensors. Meanwhile, this paper also analyzes the detection efficiency and clinical application of these biosensors. Finally, we summarize the current challenges and future development directions of the different types of biosensors involved in the discussion.
期刊介绍：
Biosensors and Bioelectronics: X, an open-access companion journal of Biosensors and Bioelectronics, boasts a 2020 Impact Factor of 10.61 (Journal Citation Reports, Clarivate Analytics 2021). Offering authors the opportunity to share their innovative work freely and globally, Biosensors and Bioelectronics: X aims to be a timely and permanent source of information. The journal publishes original research papers, review articles, communications, editorial highlights, perspectives, opinions, and commentaries at the intersection of technological advancements and high-impact applications. Manuscripts submitted to Biosensors and Bioelectronics: X are assessed based on originality and innovation in technology development or applications, aligning with the journal's goal to cater to a broad audience interested in this dynamic field.
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