家族史和种系遗传风险单核苷酸多态性对有利风险前列腺癌长期预后的影响

The Journal of Urology Pub Date : 2024-04-10 DOI:10.1097/ju.0000000000003927

Florian Rumpf, Anna Plym, Jane B Vaselkiv, Kathryn L Penney, Mark A Preston, Adam S Kibel, Lorelei A Mucci, Keyan Salari

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引用次数: 0

摘要

家族史和种系遗传风险单核苷酸多态性（SNPs）已分别被证明可对前列腺癌的终生风险进行分层。在此，我们评估了前列腺癌及其他相关癌症家族史和种系遗传风险 SNPs 在高危前列腺癌患者中的综合预后价值。

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Impact of Family History and Germline Genetic Risk Single Nucleotide Polymorphisms on Long-Term Outcomes of Favorable-Risk Prostate Cancer.

Family history and germline genetic risk single nucleotide polymorphisms (SNPs) have been separately shown to stratify lifetime risk of prostate cancer. Here, we evaluate the combined prognostic value of family history of prostate and other related cancers and germline risk SNPs among patients with favorable-risk prostate cancer.

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The Journal of Urology

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