预防性抗生素在预防缺血性卒中患者卒中相关肺炎中的作用

Life and Science Pub Date : 2024-01-15 DOI:10.37185/lns.1.1.465

Muhamad Jawad Aslam, Muhammad Amir, Tahir Mukhtar Sayed, Asif Hashmat, Maryam Hussain, Minahil Fatima

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引用次数: 0

摘要

研究目的比较使用预防性抗生素和未使用预防性抗生素的患者发生中风相关肺炎的频率：比较性横断面研究：研究地点和时间：研究于2022年8月1日至2023年1月31日在巴基斯坦白沙瓦市联合军事医院（CMH）内科进行：我们纳入了 250 名缺血性脑卒中患者，并将其分为 A 组（"预防组"）和 B 组（"无预防性抗生素组"）。入院 7 天后，通过临床检查和胸部 X 光片评估患者是否患有 "卒中相关肺炎（SAP）"。数据使用社会科学统计软件包 22 进行分析。定性变量使用频率和百分比，定量数据使用中位数（IQR），因为数据不呈正态分布，且包含异常值；与平均值和标准差相比，使用中位数和 IQR 更适合描述数据的中心倾向和分布：在我们的研究中，患者的年龄中位数为 68（46-83）岁。61（24.40%）名患者为男性，189（75.60%）名患者为女性。体重指数中位数为 31 (19-44) kg/m2。123（49.20%）名患者患有糖尿病，96（38.40%）名患者患有高血压。我们发现，在 "预防性抗生素 "组（A）中，9 名（7.20%）患者出现 SAP，而在 "无预防性抗生素 "组（B）中，SAP 的发生率为 34（27.20%）（P< 0.001）：结论：对 "缺血性卒中 "患者使用预防性抗生素可降低 "卒中相关肺炎 "的发病率，从而改善预后。因此，所有入院的缺血性脑卒中患者都应使用抗生素。如何引用此文：Aslam MJ, Amir M, Sayed TM, Hashmat A, Hussain M, Fatima M.预防性抗生素在预防缺血性中风患者中风相关肺炎中的作用。生命与科学》。2024; 5(1):82-88. doi: http://doi.org/10.37185/LnS.1.1.465

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Role of Prophylactic Antibiotics in Preventing Stroke-Associated Pneumonia in Patients with Ischemic Stroke

Objective: To compare the frequency of stroke-associated pneumonia in patients given prophylactic antibiotics versus those not given prophylactic antibiotics.Study Design: Comparative Cross-sectional study.Place and Duration of Study: The study was carried out at the Department of Internal Medicine, Combined st st Military Hospital (CMH), Peshawar, Pakistan from 1 August 2022 to 31 January 2023.Methods: We included 250 ischemic stroke patients and divided them into groups A, “Prophylactic group,” and B, “no prophylactic antibiotics group.” Patients were assessed at 7 days after admission for presence of “stroke associated pneumonia (SAP)” through clinical examination and chest X-rays. Data were analyzed using a statistical package for social sciences 22. For qualitative variables, frequency and percentages were used, whereas for quantitative data, the median (IQR) was used as the data were not normally distributed and contained outliers; using the median and IQR can be more appropriate for describing the central tendency and spread of the data compared to the mean and standard deviation.Results: In our study, the median age of the patients was 68(46-83) years. 61 (24.40%) of the patients were male while 189(75.60%) were female. The median BMI was 31 (19-44) kg/m2. Diabetes was present in 123 (49.20%) patients and 96(38.40%) had hypertension. We found that in the the “prophylactic antibiotics” group (A), 9 (7.20%) patients developed SAP, while in the “no prophylactic antibiotics” group (B) frequency of SAP was 34 (27.20%) (p< 0.001).Conclusion: Prophylactic antibiotics used in “ischemic stroke” patients provide better outcomes by reducing the incidence of “stroke-associated pneumonia”. Therefore, it should be given to all patients admitted to the hospital with ischemic CVA. How to cite this: Aslam MJ, Amir M, Sayed TM, Hashmat A, Hussain M, Fatima M.Role of Prophylactic Antibiotics in Preventing Stroke Associated Pneumonia in Patients with Ischemic Stroke. Life and Science. 2024; 5(1): 82-88. doi: http://doi.org/10.37185/LnS.1.1.465

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