重度痤疮患者:治疗展望

Q4 Medicine
Tatyana Trapeznikova, O. Letyaeva, Oleg . Ziganshin, Valeria Gubina
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引用次数: 0

摘要

痤疮是一种常见的皮肤病,发病高峰在 12 岁至 25 岁之间。皮肤(尤其是面部)容易出现炎症,导致心理情绪失衡,大大降低了患者的生活质量。在 95% 的病例中,痤疮的结果是形成卡他性畸形,治疗往往需要数年时间。如果存在炎症因素,治疗的目的应是确保疾病的长期缓解,包括防止形成新的疤痕。这项研究旨在确定使用异维A酸系统治疗痤疮的有效性和安全性。文章以临床病例为基础,介绍了全身使用异维A酸治疗严重痤疮和对标准疗法有抵抗力的痤疮的结果。事实证明,使用异维A酸所带来的益处远远大于可能出现的副作用风险,尤其是在患者皮肤容易结疤的情况下。介绍了有关卡他性畸形的病因和发病机制的最新数据。综述了痤疮后环状畸形的现代矫正技术。临床证明,异维A酸对重度痤疮具有高效、安全的治疗效果。使用异维A酸治疗痤疮不仅有效,还能降低疤痕形成的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A patient with severe acne: therapy perspectives
Acne is a common dermatological disease that peaks between 12 and 25. The tendency of inflammatory elements to appear on the skin, especially the face, leads to psycho-emotional imbalance and significantly reduces the patient’s quality of life. In 95% of cases, the outcome of acne is the formation of cicatricial deformities, the treatment of which often takes years. If inflammatory elements are present, treatment should be aimed at ensuring a long-term remission of the disease, including preventing the formation of new scars. This work aims to determine the efficacy and safety of acne treatment using systemic isotretinoin. The article presents the results of systemic isotretinoin use in severe forms of acne and acne that is resistant to standard treatments based on clinical cases. It was proved that the benefits obtained from isotretinoin usage are much more significant than the possible risk of side effects, especially if the patient’s skin tends to scar. The latest data on the etiology and pathogenesis of cicatricial deformities is presented. A review of modern techniques for the correction of post-acne cicatricial deformities was carried out. Isotretinoin is clinically proven to be highly effective and safety safe for both severe acne. The use of isotretinoin to treat acne is effective and reduces the risk of scarring.
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
40
审稿时长
8 weeks
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