治疗帕金森病的各种草药疗法:综述

Q3 Pharmacology, Toxicology and Pharmaceutics
Mohammed Nazish Quasmi, Pooja Pooja, Sumit Kumar
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引用次数: 0

摘要

帕金森病(PD)是一种以多巴胺能神经元水平下降为特征的神经变性疾病。帕金森病的一些身体症状包括静止性震颤、僵硬、运动迟缓或运动障碍、不稳定和僵直。帕金森氏症患者的大脑SN和其他区域会受到损伤。活性氧非常重要,氧化应激可能与该疾病(ROS)有关。许多草药疗法中都含有具有抗氧化功效的活性成分。因此,草药疗法在帕金森病治疗中的重要性不容忽视。本综述的主要目的是研究帕金森病(PD)的发病机理,并描述几种潜在草药提取物对其发病机理的作用,为治疗奠定基础。我们还深入探讨了每种草药中存在的对治疗帕金森病有用的化学成分。这些草药是白芨(MP,卡皮卡丘)、积雪草(CA,曼都卡帕尼)、巴戟(BM,婆罗米)、肉桂(CV,肉桂)、西达脐叶(SC,巴拉)、胡桃精(JS,核桃)、山茶(CS,绿茶)、姜黄(CL,姜黄)、睡茄(PL,葛根)。未来成功治疗帕金森氏症的药物开发可能会受益于本综述的研究结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Various herbal remedies for the management of Parkinson’s disease: A Review
Parkinson's disease (PD) is a condition of neurodegeneration characterised by the decreased levels of dopaminergic neurons. Some of the physical issues with PD include resting tremors, stiffness, bradykinesia or akinesia, instability, and freezing. Damage to the brain's SN and other regions is present in PD. Reactive oxygen species are important and oxidative stress may be related to the disorder (ROS). There are active components in many herbal treatments that have been found to have antioxidant benefits. Therefore, the importance of herbal remedies in the management of PD cannot be undermind. The major goal of the current review is to examining the Parkinson’s disease pathogenesis (PD) and describes function of several potential herbal extracts on its pathogenesis, which may serve as the foundation for treatment. We also go into the chemical components that are present in each herb and useful in treating Parkinson's disease. These herbs are Mucuna pruriens (MP, kapikacchu), Centella asiatica (CA, Mandookaparni), Bacopa monnieri (BM, Brahmi), Cinnamomum verum (CV, cinnamon), Sida cordifolia (SC, bala), Juglandis semen (JS, walnut), Camellia sinens (CS, green tea), Curcuma longa (CL, turmeric), Withania somnifera (PL, kudzu). Future drug development for the successful treatment of PD may benefit from the findings of the current review.
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来源期刊
Research Journal of Pharmacy and Technology
Research Journal of Pharmacy and Technology Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
CiteScore
1.40
自引率
0.00%
发文量
0
期刊介绍: Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.
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