硬膜外穿刺与传统硬膜外技术的分娩镇痛起始:确定 90% 患者布比卡因有效剂量的随机双向硬币顺序分配试验

A. Maeda, D. Villela-Franyutti, M. Lumbreras-Marquez, A. Murthy, K.G. Fields, S. Justice, L. Tsen
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引用次数: 0

摘要

(Anesth Analg. 2023. doi: 10.1213/ANE.0000000000006691)神经轴分娩镇痛包括传统硬膜外(EPL)技术以及脊髓硬膜外和硬膜穿刺硬膜外(DPE)联合技术。通过研究发现,与 EPL 技术相比,DPE 技术具有一些优势。一项研究采用了偏向硬币上下分配法,以确定使用 DPE 和 EPL 技术对 90% 的产妇(ED90)进行初始镇痛所需的布比卡因有效剂量。根据假设,DPE 与 EPL 相比,所需的布比卡因剂量更低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Labor Analgesia Initiation With Dural Puncture Epidural Versus Conventional Epidural Techniques: A Randomized Biased-Coin Sequential Allocation Trial to Determine the Effective Dose for 90% of Patients of Bupivacaine
(Anesth Analg. 2023. doi: 10.1213/ANE.0000000000006691) Neuraxial labor analgesia includes the conventional epidural (EPL) technique as well as the combined spinal epidural and dural puncture epidural (DPE) techniques. Some advantages to the DPE technique have been discovered through research in comparison to the EPL technique. A study was conducted using a biased-coin up-down allocation method to determine the effective dose of bupivacaine needed to achieve initial analgesia in 90% of women in labor (ED90) using the DPE and EPL techniques. It was hypothesized that a lower bupivacaine dose would be needed with the DPE versus the EPL.
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