喉黄质鳞状细胞癌:尸检确诊的窒息死亡的不寻常原因

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL
M. Osama, Kavita Gaur, Kiran Agarwal, Lakshmilekiya Sekar, Shrayash Singh, Sukhdeep Singh
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引用次数: 0

摘要

溶解性鳞状细胞癌(ASCC)是鳞状细胞癌(SCC)的一种不常见的组织病理学变异。这种肿瘤通常发生在头颈部暴露在阳光下的皮肤区域。可能发生在粘膜部位的报道很少。虽然这种恶性肿瘤在皮肤部位的预后良好,但与之形成鲜明对比的是,粘膜受累部位的预后较差。在此,我们将探讨一例有趣的病例:一名 35 岁男子因声门区息肉样肿块堵塞气道而窒息死亡。随后,根据组织病理学和免疫组化结果,死因被诊断为 ASCC。此外,该报告还强调了这种变异型 SCC 在不常见部位的罕见性,从而使其成为文献中报道的第三例病例。本病例的另一个有趣事实是,大多数已发表的文献报告都是在死前检查时描述和诊断出这种罕见的变异;相反,在死后诊断出 ASCC 的病例却非常罕见,这在历史上尚属首例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Acantholytic squamous cell carcinoma of larynx: An unusual cause of asphyxial death diagnosed on autopsy
Acantholytic squamous cell carcinoma (ASCC) is an uncommon histopathological variant of squamous cell carcinoma (SCC). This tumor commonly occurs in the sun exposed areas of skin at the head and neck location. The possible occurrence at mucosal sites has seldom been reported. Although, this malignant tumor has an excellent prognosis in the skin, in sharp contrast, mucosal involvement carries a worse prognosis. Here, we explore an intriguing case of an asphyxial death of a 35-year-old man due to a polypoidal mass occluding the airway in the glottic region. Subsequently, based on the histopathological and immunohistochemical findings, the cause of death was diagnosed as ASCC based on histopathological and immunohistochemical findings. Furthermore, this report also highlights the rarity of this variant of SCC at an uncommon location, thus making it the third case ever reported in literature. The other interesting fact about this case is that most of the published reports in the literature have described and diagnosed this rare variant on antemortem examination; contrarily, a postmortem diagnosis of ASCC is exceptional, making it the first report ever in history.
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来源期刊
Journal of Laboratory Physicians
Journal of Laboratory Physicians MEDICINE, GENERAL & INTERNAL-
自引率
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发文量
99
审稿时长
31 weeks
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