评注第 2 部分:提高生育能力的减肥干预措施a 当前证据综述

Emma Schneider, Dr Oliver Hamer, Dr Chris Smith, James Hill
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摘要

不孕不育是一个普遍存在的问题,据估计影响着高达 17.5% 的全球人口。有证据表明,导致女性不孕的最常见原因是排卵障碍。尽管如此,饮食模式、饮酒、吸烟和肥胖等生活方式因素仍是关键的决定因素,这些因素已被证明会影响女性的生理机能,并大大降低受孕几率。肥胖已被广泛认为是对女性卵巢刺激产生负面影响的重要因素,并与多种生殖障碍有关。尽管不孕不育治疗方法有所改进,但肥胖仍然是不孕不育诊所面临的一项挑战,因为肥胖人群的妊娠结局较差。在本文中,我们将探讨减肥对女性生育力的影响,并回顾各种已被证明能有效减少肥胖和改善生殖结果的策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
COMMENTARY PART 2: WEIGHT LOSS INTERVENTIONS FOR IMPROVING FERTILITYA SYNTHESIS OF CURRENT EVIDENCE
Infertility is a widespread issue which is estimated to affect up to 17.5% of the global population. Evidence suggests that the most common causes of female infertility are ovulation disorders. That said, lifestyle factors such as dietary patterns, alcohol consumption, smoking and obesity are key determinants which have been shown to impact female physiology and significantly decrease the chances of conception. Obesity has been widely recognised as a significant factor that negatively impacts ovarian stimulation in women and is associated with several reproductive disorders. Despite improvements in fertility treatments, obesity remains a challenge particularly for fertility clinics because of the poorer pregnancy outcomes observed within the population. In this article, we will explore the effects of weight loss on female fertility and review the various strategies that have been shown to be effective in reducing obesity and improving reproductive outcomes.
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