溃疡性结肠炎手术

IF 1.4 3区 医学 Q3 PEDIATRICS
Brielle Ochoa, Lisa McMahon
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引用次数: 0

摘要

溃疡性结肠炎(UC)在儿童患者中的表现更严重,病情进展更快,因此与成人相比,儿童患者更需要手术治疗。虽然新的生物疗法推动了 UC 的内科治疗,但当疾病发展为症状恶化或持续存在、血流动力学不稳定或败血症时,外科手术仍将发挥重要作用。手术治疗的目标是尽可能通过功能性肠袋恢复肠道的连续性。虽然有关 UC 儿童患者的研究文献越来越多,但高水平的证据研究却很有限,大多数建议都是基于成人研究提出的。与成人类似,建立回肠袋的儿科患者也需要进行复发疾病监测和癌症监测。儿科患者的特殊问题包括发育监测和青春期后向成人护理的适当过渡。本综述包括手术治疗的适应症、分阶段手术方法概述以及三阶段手术方法的技术细节。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Surgery for ulcerative colitis

Ulcerative colitis (UC) has a more severe presentation and rapid progression in pediatric patients, resulting in a greater need for surgical intervention compared to adults. Though medical management of UC has advanced with new biologic therapies, surgery continues to play an important role when disease progresses in the form of worsened or persistent symptoms, hemodynamic instability, or sepsis. The goals of surgical management are to restore intestinal continuity with a functional pouch when possible. While the literature has been growing regarding studies of pediatric patients with UC, high level of evidence studies are limited and most recommendations are based on adult studies. Similar to adults, pediatric patients who have ileal pouches created require surveillance for recurrent disease and cancer surveillance. Unique issues for pediatric patients include monitoring of growth and appropriate transition to adult care after adolescence. This review includes indications for surgical management, overview of staged surgical approaches, and the technical details of the three-stage approach.

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来源期刊
Seminars in Pediatric Surgery
Seminars in Pediatric Surgery PEDIATRICS-SURGERY
CiteScore
2.80
自引率
5.90%
发文量
57
审稿时长
>12 weeks
期刊介绍: Seminars in Pediatric Surgery provides current state-of-the-art reviews of subjects of interest to those charged with the surgical care of young patients. Each bimontly issue addresses a single topic with articles written by the experts in the field. Guest editors, all noted authorities, prepare each issue.
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