奥昔诺龙对急性脊髓损伤患者体重减轻和肌肉质量的影响

IF 0.4 4区医学 Q4 NUTRITION & DIETETICS

Topics in Clinical Nutrition Pub Date : 2024-03-25 DOI:10.1097/tin.0000000000000353

Stacy L Pelekhaty, Mehrnaz Pajoumand, Maureen Scarboro, Rosemary Kozar

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引用次数: 0

摘要

为了研究奥昔诺龙对急性脊髓损伤（aSCI）后体重和瘦体重（LBM）减少的影响，本观察性研究将接受奥昔诺龙治疗的患者与历史对照组进行了比较。研究人员收集了患者的年龄、性别、损伤程度、入院和出院时的人体测量数据、营养干预措施、住院时间、肝功能检测、入院时胸锁乳突肌面积（SMA）与身高的比例以及随访计算机断层扫描结果。其中包括 20 名接受奥昔诺龙治疗的患者和 20 名对照组患者。奥昔诺龙患者体重下降较少，但在 SMA 方面未观察到差异。奥昔诺龙减少了 aSCI 后的体重减轻，但还需要更大规模的研究来评估其对 LBM 的影响。

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The Effect of Oxandrolone on Weight Loss and Muscle Mass in Acute Spinal Cord Injury Patients

To investigate the impact of oxandrolone on weight and lean body mass (LBM) loss after acute spinal cord injury (aSCI), this observational study compared patients who received oxandrolone with historical controls. Age, sex, injury level, admission and discharge anthropometrics, nutrition interventions, length of stay, liver function tests, sternocleidomastoid muscle area (SMA) indexed to height on admission, and follow-up computed tomography scans were collected. Twenty patients receiving oxandrolone and 20 controls were included. Oxandrolone patients lost less weight; however, no differences were observed in SMA. Oxandrolone reduced weight loss following aSCI, but larger studies are needed to assess its impact on LBM.

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来源期刊

Topics in Clinical Nutrition NUTRITION & DIETETICS-

CiteScore

0.90

自引率

20.00%

发文量

期刊介绍： Topics in Clinical Nutrition (TICN) is a peer-reviewed, quarterly journal designed as a resource for the continuing education and clinical practice of dietitians and nutritionists. Each issue addresses topics of interest primarily to dietitians and nutritionists, students and interns in professional training programs and other health care personnel involved in the nutritional care of patients. Articles include translational research reports (work that applies new knowledge to practical effect), practice projects, evidence-based literature reviews, case studies and book reviews, and articles that highlight education theory and applied research which share the tools and techniques of nutrition and dietetics education.