应用间充质干细胞治疗椎间盘退行性病变

Deby Susanti Pada Vinski, Carles Siagian, Andi Kurniawan Nugroho, Marhaen Hardjo, Natasha Cinta Vinski
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引用次数: 0

摘要

在人的一生中,脊柱会随着生理轴向负荷的变化而不断发生变化。年龄的增长也是病理性退行性变化的一个原因。脊柱退行性疾病是很多人抱怨的一种疾病,需要适当而有效的治疗。椎间盘退行性病变是全世界腰背疼痛和残疾的最常见原因,涉及各个年龄段和社会经济地位的人群。本研究旨在解释和分析间充质干细胞疗法在治疗椎间盘退行性病变方面的有效性。采用的研究方法是病例研究,间充质干细胞疗法提供了利用干细胞技术改变椎间盘退行性病变自然恢复的潜力。文斯基再生中心(Vinski Regenerative Center)诊所对多名患者进行了病例研究。研究结果表明,干细胞有可能成为治疗腰背痛和椎间盘退行性疾病的理想非手术疗法,因为干细胞能够分化成各种结缔组织细胞,并能恢复受损组织。然而,仍需进行长期临床研究,特别是侧重于干细胞疗法对椎间盘退行性疾病的安全性和有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Application of Mesenchymal Stem Cell for Degenerative Disc Disease
During a person's life, the spine will experience continuous changes in response to physiological axial loads. Increasing age is also a cause of pathological degenerative changes. Degenerative disease of the spine is a condition that many people complain about and requires appropriate and effective treatment. Degenerative disc disease is the most common cause of low back pain and disability worldwide, involving people of all ages and socioeconomic statuses. This study aims to explain and analyze the effectiveness of Mesenchymal Stem Cell therapy in treating Degenerative Disc Disease. The research method used is a case study where  Mesenchymal Stem Cell therapy offers the potential to modify the natural recovery of Degenerative Disc Disease using stem cell-based technology. Case studies were carried out at the Vinski Regenerative Center clinic, on several patients. And the results are that stem cells have the potential to be an ideal non-surgical treatment for low back pain and degenerative disc disease, because of their ability to differentiate into various connective tissue cells and their ability to restore damaged tissue and the results of case studies have proven to tend to improve the condition. However, long-term clinical studies are still needed, specifically focusing on the safety and efficacy of stem cell therapy in degenerative disc disease.
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