Andrea C. Bardales, Quynh Vo, Dmitry M Kolpashchikov
{"title":"单子{NOT}和双子{YES; NOT}门在 DNA 集成计算电路中充当功能完整集","authors":"Andrea C. Bardales, Quynh Vo, Dmitry M Kolpashchikov","doi":"10.3390/nano14070600","DOIUrl":null,"url":null,"abstract":"A functionally complete Boolean operator is sufficient for computational circuits of arbitrary complexity. We connected YES (buffer) with NOT (inverter) and two NOT four-way junction (4J) DNA gates to obtain IMPLY and NAND Boolean functions, respectively, each of which represents a functionally complete gate. The results show a technological path towards creating a DNA computational circuit of arbitrary complexity based on singleton NOT or a combination of NOT and YES gates, which is not possible in electronic computers. We, therefore, concluded that DNA-based circuits and molecular computation may offer opportunities unforeseen in electronics.","PeriodicalId":508599,"journal":{"name":"Nanomaterials","volume":"12 2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Singleton {NOT} and Doubleton {YES; NOT} Gates Act as Functionally Complete Sets in DNA-Integrated Computational Circuits\",\"authors\":\"Andrea C. Bardales, Quynh Vo, Dmitry M Kolpashchikov\",\"doi\":\"10.3390/nano14070600\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A functionally complete Boolean operator is sufficient for computational circuits of arbitrary complexity. We connected YES (buffer) with NOT (inverter) and two NOT four-way junction (4J) DNA gates to obtain IMPLY and NAND Boolean functions, respectively, each of which represents a functionally complete gate. The results show a technological path towards creating a DNA computational circuit of arbitrary complexity based on singleton NOT or a combination of NOT and YES gates, which is not possible in electronic computers. We, therefore, concluded that DNA-based circuits and molecular computation may offer opportunities unforeseen in electronics.\",\"PeriodicalId\":508599,\"journal\":{\"name\":\"Nanomaterials\",\"volume\":\"12 2\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-03-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nanomaterials\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3390/nano14070600\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nanomaterials","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/nano14070600","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
对于任意复杂度的计算电路来说,一个功能完整的布尔算子就足够了。我们将 YES(缓冲器)与 NOT(反相器)和两个 NOT 四路结(4J)DNA 门连接起来,分别得到了 IMPLY 和 NAND 布尔运算函数,每个函数都代表了一个功能完整的门。研究结果表明,基于单个 NOT 或 NOT 与 YES 门的组合,可以创建任意复杂度的 DNA 计算电路,而这在电子计算机中是不可能实现的。因此,我们得出结论,基于 DNA 的电路和分子计算可能会带来电子学无法预见的机遇。
Singleton {NOT} and Doubleton {YES; NOT} Gates Act as Functionally Complete Sets in DNA-Integrated Computational Circuits
A functionally complete Boolean operator is sufficient for computational circuits of arbitrary complexity. We connected YES (buffer) with NOT (inverter) and two NOT four-way junction (4J) DNA gates to obtain IMPLY and NAND Boolean functions, respectively, each of which represents a functionally complete gate. The results show a technological path towards creating a DNA computational circuit of arbitrary complexity based on singleton NOT or a combination of NOT and YES gates, which is not possible in electronic computers. We, therefore, concluded that DNA-based circuits and molecular computation may offer opportunities unforeseen in electronics.