儿童轻度慢性胃炎发病率上升:单中心经验

IF 1.3 4区 医学 Q3 PATHOLOGY
Pediatric and Developmental Pathology Pub Date : 2024-05-01 Epub Date: 2024-03-28 DOI:10.1177/10935266241238625
Rohit Josyabhatla, Mary Lauren Wood, Amber Gafur, Nina Tatevian, Amanda S Tchakarov, Syed Shahrukh Hashmi, Jon Marc Rhoads, Melissa Renee Van Arsdall
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引用次数: 0

摘要

目的和方法:我们分析了10年间接受上消化道内镜检查的3批儿童的上消化道内镜和组织学检查结果。共确定了 579 名患者,其中 2011 年、2015 年和 2019 年队列中分别有 244 人(42%)、199 人(35%)和 136 人(23%)。最常见的症状和体征是腹痛、呕吐、发育不良和腹泻:随着时间的推移,有慢性胃炎组织学证据的患者人数从2011年(n = 70,29%)增加到2015年(n = 106,53%)和2019年(n = 92,68%;P P = .008),与2015年(P = .026)和2019年(P = .001)相比,2011年的低级别患者更多。对预测因素(性别、体重百分位数、付款人类型、内镜检查月份、症状持续时间、PPI暴露和内镜胃部检查结果)进行粗略比较后发现,病例与对照组之间没有差异:结论:过去十年中,我国人群中轻度慢性胃炎或非特异性胃炎的发病率明显上升。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rising Prevalence of Mild Chronic Gastritis in Children: A Single Center Experience.

Objectives and methods: We analyzed upper endoscopic and histological findings in 3 cohorts of children undergoing upper gastrointestinal endoscopy over a 10-year period. Five hundred seventy-nine patients were identified, with 244 (42%), 199 (35%), and 136 (23%) in the 2011, 2015, and 2019 cohorts, respectively. The most common symptoms and signs were abdominal pain, vomiting, failure to thrive, and diarrhea.

Results: The number of patients who had histological evidence of chronic gastritis increased from 2011 (n = 70, 29%) to 2015 (n = 106, 53%) and 2019 (n = 92, 68%; P < .001). The prevalence of "normal" endoscopic gastric findings was higher in controls (n = 247, 90%) compared to cases (n = 201, 76%; P < .001). There was a small but statistically significant difference in endoscopic esophageal grading (P = .008) over time, with lower grades being more prevalent in 2011 compared to 2015 (P = .026) and 2019 (P = .001). Crude comparisons of the predictors (sex, weight percentile, payor type, month of endoscopy, symptom duration, PPI exposure, and endoscopic stomach findings) yielded no difference between cases and controls.

Conclusions: There has been a significant rise in the prevalence of mild chronic gastritis or non-specific gastritis over the last decade in our population.

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来源期刊
CiteScore
3.70
自引率
5.30%
发文量
59
审稿时长
6-12 weeks
期刊介绍: The Journal covers the spectrum of disorders of early development (including embryology, placentology, and teratology), gestational and perinatal diseases, and all diseases of childhood. Studies may be in any field of experimental, anatomic, or clinical pathology, including molecular pathology. Case reports are published only if they provide new insights into disease mechanisms or new information.
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