古老的 RNA 是如何存活下来的，以及我们能从中学到什么。

IF 81.3 1区生物学 Q1 CELL BIOLOGY

Nature Reviews Molecular Cell Biology Pub Date : 2024-03-28 DOI:10.1038/s41580-024-00726-y

Marc R. Friedländer, M. Thomas P. Gilbert

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引用次数: 0

摘要

虽然 RNA 通常是瞬时的，但通过低温、干燥或化学处理保存后，RNA 可以在死后持续存在。在这篇评论中，我们将讨论如何利用古 RNA 研究至少可追溯到上个冰河时期的（前）历史病毒、植物和动物的基因表达。弗里德兰德（Friedländer）和吉尔伯特（Gilbert）介绍了病毒、植物和动物的古 RNA 研究，以及它如何为我们提供（前）历史基因表达的信息。

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How ancient RNA survives and what we can learn from it

Although normally transient, RNA can persist postmortem when preserved by cold, desiccation or chemical treatment. In this Comment, we discuss how ancient RNA enables the study of gene expression of (pre)historic viruses, plants and animals going back at least as far as the last Ice Age. Friedländer and Gilbert introduce the study of ancient RNA of viruses, plants and animals, and how it can inform us of (pre)historic gene expression.

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来源期刊

Nature Reviews Molecular Cell Biology 生物-细胞生物学

CiteScore

173.60

自引率

0.50%

发文量

118

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Molecular Cell Biology is a prestigious journal that aims to be the primary source of reviews and commentaries for the scientific communities it serves. The journal strives to publish articles that are authoritative, accessible, and enriched with easily understandable figures, tables, and other display items. The goal is to provide an unparalleled service to authors, referees, and readers, and the journal works diligently to maximize the usefulness and impact of each article. Nature Reviews Molecular Cell Biology publishes a variety of article types, including Reviews, Perspectives, Comments, and Research Highlights, all of which are relevant to molecular and cell biologists. The journal's broad scope ensures that the articles it publishes reach the widest possible audience.