羊膜移植是化脓性链球菌坏死性角结膜炎多模式疗法的一部分。

IF 1.2 4区医学 Q3 OPHTHALMOLOGY

Journal of Aapos Pub Date : 2024-06-01 DOI:10.1016/j.jaapos.2024.103900

Kelly L. Ruland MD , Natalya Beneschott MD , C. Buddy Creech MD, MPH , Allison Umfress MD

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引用次数: 0

摘要

化脓性链球菌（A 组β-溶血性链球菌，GABHS）会引起一系列人类感染，包括坏死性筋膜炎和中毒性休克综合征，因为它产生的外毒素会破坏宿主细胞，促进免疫逃避，并成为 T 细胞的超级抗原。GABHS 结膜炎非常罕见。我们报告了一例 3 岁儿童的膜性结膜炎病例，该病例接受了靶向杀菌抗菌剂、毒素合成抑制剂和羊膜移植的综合治疗。

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Amniotic membrane transplantation as part of a multimodal management approach to Streptococcus pyogenes necrotizing keratoconjunctivitis

Streptococcus pyogenes (group A beta-hemolytic Streptococcus, GABHS) causes a range of human infections, including necrotizing fasciitis and toxic shock syndrome, because it produces exotoxins that damage host cells, facilitate immune evasion, and serve as T cell superantigens. GABHS conjunctivitis is rare. We report a case of membranous conjunctivitis in a 3-year-old child who was treated with a combination of targeted bactericidal antimicrobials, toxin-synthesis inhibition, and amniotic membrane transplantation.

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来源期刊

Journal of Aapos 医学-小儿科

CiteScore

2.40

自引率

12.50%

发文量

159

审稿时长

55 days

期刊介绍： Journal of AAPOS presents expert information on children''s eye diseases and on strabismus as it affects all age groups. Major articles by leading experts in the field cover clinical and investigative studies, treatments, case reports, surgical techniques, descriptions of instrumentation, current concept reviews, and new diagnostic techniques. The Journal is the official publication of the American Association for Pediatric Ophthalmology and Strabismus.