AIRE 以富含 Z-DNA 的定向启动子为目标。

IF 39.1 1区生物学 Q1 GENETICS & HEREDITY

Nature Reviews Genetics Pub Date : 2024-03-27 DOI:10.1038/s41576-024-00728-8

Kirsty Minton

引用次数: 0

摘要

自然》（Nature）杂志上的一篇论文报告了转录因子 AIRE 目标特异性的 "Z-DNA-锚定 "模型，该模型涉及双链断裂处的启动子定位。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

AIRE targets poised promoters enriched for Z-DNA

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AIRE targets poised promoters enriched for Z-DNA

A paper in Nature reports a ‘Z-DNA-anchored’ model for the target specificity of the transcription factor AIRE, involving promoter poising at double-strand breaks.

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来源期刊

Nature Reviews Genetics 生物-遗传学

CiteScore

57.40

自引率

0.50%

发文量

113

审稿时长

6-12 weeks

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