过去三十年赫罗纳省急性心肌梗死发病率和致死率分析

IF 5.9 2区 医学 Q2 Medicine
Anna Camps-Vilaró , Isaac Subirana , Roberto Elosua , Iván Palomo , Juan Sanchis , Helena Tizón-Marcos , Miguel Cainzos-Achirica , Joan Sala , Rafael Masia , Rafel Ramos , Irene R. Dégano , Jaume Marrugat
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引用次数: 0

摘要

导言和目标心肌梗死(MI)发病率和病死率趋势具有很强的信息量,但在人口层面却相对缺乏检验。这项工作的目的是估计赫罗纳 35-74 岁人口的心肌梗死发病率和病死率,并确定其 30 年趋势(1990-2019 年)。在 2008 年至 2019 年期间,我们将赫罗纳医院的出院病例(n = 4 974 977)与这一时期的死亡率登记(n = 70 405)联系起来。我们的连接算法选择了关键的 MI 诊断代码,并删除了重复的代码。在重叠年份(2008-2009 年),我们使用卡方检验比较了链接算法和 REGICOR 登记的估计值。我们估算了标准化 MI 发病率和 28 天病死率的年度百分比变化 (APC),并使用连接点回归分析了其趋势。我们观察到 MI 发病率呈明显下降趋势。从 1990 年到 2019 年,女性的发病率为 APC,-0.96%(95% 置信区间 (95%CI),-1.4 到 -0.53);从 1994 年到 2019 年,男性的发病率为 -4.2%(95%CI,-5.5 到 -3.0)。从 1995 年到 2003 年,女性病例死亡率的最大降幅为-3.8%(95%CI,-5.1 到-2.5),从 1995 年到 2004 年,男性病例死亡率的最大降幅为-2.4%(95%CI,-2.9 到-1.9),这主要是由于院前病例死亡率的下降:-结论在 1990 年至 2019 年期间,赫罗纳的心肌梗死发病率和病死率均有所下降。发病率呈现缓慢但持续的下降趋势,而病死率在过去十年中才趋于稳定,尤其是在女性中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Análisis de la incidencia y la letalidad del infarto agudo de miocardio en la provincia de Girona durante las tres últimas décadas

Introduction and objectives

Myocardial infarction (MI) incidence and case fatality trends are highly informative but relatively untested at the population level. The objective of this work was to estimate MI incidence and case fatality in the Girona population aged 35-74 years, and to determine their 30-year trends (1990-2019).

Methods

The REGICOR (Girona Heart Registry) monitored MI incidence and case fatality rates from 1990 to 2008. For the period 2008 to 2019, we linked discharges from Girona hospitals (n = 4 974 977) and mortality registry (n = 70 405) during this period. Our linkage algorithm selected key MI diagnostic codes and removed duplicates. Estimates from the linkage algorithm and the REGICOR registry were compared using chi-square tests for overlapping years (2008-2009). We estimated the annual percent change (APC) of standardized MI incidence and 28-day case fatality, and analyzed their trends using joinpoint regression.

Results

MI incidence and case fatality estimates were similar in the linkage algorithm and the REGICOR registry. We observed significant decreasing trends in the incidence of MI. The trend was APC, -0.96% (95% confidence interval (95%CI), –1.4 to –0.53) in women from 1990 to 2019 and –4.2% (95%CI, –5.5 to –3.0) in men from 1994 to 2019. The largest decrease in case fatality was –3.8% (95%CI, -5.1 to –2.5) from 1995 to 2003 in women and –2.4% (95%CI, –2.9 to –1.9) from 1995 to 2004 in men, mainly due to prehospital case fatality declines: -1.8% (95%CI, –2.6 to –1.1) in men and –3.2% (95%CI, –4.6 to –1.8) in women.

Conclusions

In Girona, MI incidence and case fatality decreased between 1990 and 2019. The incidence showed a slow but continuous decrease while case fatality only stabilized in the last decade, particularly in women.

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来源期刊
Revista espanola de cardiologia
Revista espanola de cardiologia 医学-心血管系统
CiteScore
4.20
自引率
13.60%
发文量
257
审稿时长
28 days
期刊介绍: Revista Española de Cardiología, Revista bilingüe científica internacional, dedicada a las enfermedades cardiovasculares, es la publicación oficial de la Sociedad Española de Cardiología.
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