异常子宫出血的子宫内膜病理学研究

Anjali Dubey, Pratishtha Shrivastava, Konika Jain
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摘要

目的:子宫内膜病变正成为影响全球育龄妇女的最常见问题。AUB 包括多种表现形式,例如月经周期频繁、周期性出血频繁且量多、不规则出血和性交后出血。本研究旨在评估 AUB 的子宫内膜病因,并确定不同年龄组的具体病理情况。研究方法本研究是一项前瞻性横断面研究,于 2023 年 1 月至 2023 年 10 月在一家知名教学医院和研究中心的病理科对 200 名患者进行了研究。所有送检的子宫内膜活检/清宫术和子宫切除术标本均有 AUB 病史。研究结果在我们的研究中,AUB 患者的年龄从 17 岁到 71 岁不等。在 200 例患者中,90 例(45%)为围绝经期患者,其次是 68 例(34%)育龄期患者和 42 例(21%)绝经后患者。54%的 AUB 患者最常见的出血模式是月经过多。育龄组中有 28%的患者出现内分泌失调,育龄组中有 13%,围绝经期组中有 6%。在绝经后年龄组中,7.5%的妇女出现萎缩性子宫内膜。3%的育龄妇女患有慢性子宫内膜炎。结论不同年龄组妇女的异常子宫出血在组织病理学检查中表现出不同的子宫内膜形态。它们对早期发现子宫内膜癌前病变和恶性肿瘤很有价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
STUDY OF ENDOMETRIAL PATHOLOGY IN ABNORMAL UTERINE BLEEDING
Objective: Endometrial pathology is becoming the most common issue that affects women of reproductive age group worldwide. AUB encompasses a wide variety of presentations, for example, frequent menstrual cycles, frequent and heavy cyclical bleeding, irregular bleeding, and postcoital bleeding. This study was done to evaluate the endometrial causes of AUB and to determine the specific pathology in different age groups. Methods: This study was a prospective cross-sectional study conducted on 200 patients from January 2023 to October 2023 in the department of pathology in a reputed teaching hospital and research centre. All the endometrial biopsies/curretages and hysterectomy specimens sent for Histopathological examination with history of AUB were included in the study. Results: Age of the patients with AUB ranged from 17 to 71 y in our study. Out of 200 cases, 90 cases (45%) were seen in Perimenopausal group followed by 68 cases (34 %) in Reproductive age group and 42 cases (21%) in Postmenopausal age group. Menorrhagia was the most common bleeding pattern seen in 54% pf patient with AUB. In 28% in reproductive age group, hormonal imbalance was observed in 13% of reproductive age group and 6% in perimenopausal age group. Atrophic endometrium was observed in 7.5% of women in post-menopausal age group. Chronic endometritis was seen 3% of reproductive age group. Conclusion: Abnormal uterine bleeding in women belonging to different age group show variable endometrial pattern on histopathological examination. They are valuable in early detection of pre-cancerous endometrial lesions as well as malignancy.
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