估算新生儿脐带导管插入长度的新公式:观察研究

Q4 Medicine
Jennifer Webb, Sian Elliott, W. J. Watkins, Laura Stuttaford, Sujoy Banerjee, Babatunde Kayode-Adedeji, Gautam Bagga, Neha Sharma, M. Chakraborty
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引用次数: 0

摘要

目的:临床医生目前用于估算脐部导管插入长度的公式并不准确。我们的目的是建立一个新模型,以提高估计脐部导管插入长度的准确性。研究设计:这是一项多中心前瞻性观察研究,研究对象是新生儿病房收治的因临床原因需要插入脐导管的新生儿。在英国南威尔士的三个三级新生儿科室收集了人口统计学数据、导管相关测量数据和新的外部长度测量数据--到脐部的胸骨切迹。我们使用广义线性模型来估计外部长度、出生体重、妊娠和头围与导管长度的拟合度,并得出一个公式。通过比较每个等式的 r 2 值来估计最佳拟合度。结果:根据新的数学公式分析了 113 名婴儿的静脉和动脉导管数据。对于脐动脉导管插入术[[公式:见正文]]和脐静脉导管插入术(UVC)[[公式:见正文]],基于出生体重的二次模型被认为是预测导管插入长度的最佳拟合模型。然而,在所有解释变量中,脐静脉导管的总体拟合效果较差(y = 脐静脉导管的估计插入长度,单位为厘米;x = 出生体重,单位为千克)。结论我们的前瞻性多中心观察研究发现,基于出生体重的二次模型是估计新生儿脐管插入长度的最佳拟合模型。这是一项新发现,是对早期基于出生体重的线性模型的进一步发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A New Formula for Estimating Insertion Length of Umbilical Catheters in Neonates: An Observational Study
Objective: Current formulae used by clinicians to estimate the insertion length of umbilical catheters are inaccurate. We aimed to derive a new model that could improve accuracy in estimating the insertion length of umbilical catheters. Study design: This was a multi-centre prospective observational study of neonates admitted to neonatal units and needing umbilical line(s) inserted for clinical reasons. Demographic data, catheter-related measurements and a new external length measurement—sternal notch to the umbilicus, were collected at three tertiary-level neonatal units in South Wales, UK. Generalised linear models were used to estimate the fit of the external length, birthweight, gestation and head circumference with catheter length and to derive a formula. The best fit was estimated by comparing r 2 values for each equation. Results: Data from 113 infants for each venous and arterial line were analysed for the new mathematical formulae. For both umbilical arterial catheterisation [[Formula: see text] and umbilical venous catheter (UVC) [[Formula: see text]], a quadratic model based on birthweight was found to have the best fit for predicting the insertion length of the catheters. However, the overall fit for UVCs was poorer for all explanatory variables ( y = estimated insertion length of the umbilical catheter in cm, x = birthweight in kg). Conclusion: Our prospective multi-centre observational study identified a quadratic model based on birthweight as the best fit for estimating the insertion length of umbilical lines in neonates. This is a new finding and further development on earlier birthweight-based linear models.
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来源期刊
Journal of Neonatology
Journal of Neonatology Medicine-Pediatrics, Perinatology and Child Health
CiteScore
0.30
自引率
0.00%
发文量
55
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