{"title":"从 Icacina trichantha oliv TUBER 的氯醛原油提取物中分离、鉴定一种呋喃衍生物并确定其抗溃疡效力。","authors":"O. U. Akoh, B. Anyanwu, O. M. Mac-Kalunta","doi":"10.46602/jcsn.v49i1.956","DOIUrl":null,"url":null,"abstract":"Spectroscopic analysis of a pure isolate (OAU 2, a furan derivative) by column chromatography from the chloroform crude extract of Icacina trichantha tuber was done using FT-IR, 1HNMR, 13CNMR, COSY and was established by literature as well as the investigation of antimycobacterial potency. This anitmycobacterial activity revealed that this isolate actually has activity against DR-TB Strain and H37RV Strain which are American type culture collection strain and multi-drug resistant strains of M. tuberculosis being the test organisms. Hence, confirming the folk believe of the use of I. trichantha tuber in the treatment of “serious cough”","PeriodicalId":15357,"journal":{"name":"Journal Of Chemical Society Of Nigeria","volume":"27 45","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ISOLATION, CHARACTERIZATION AND ANTIMYCOBACTERIAL POTENCY OF A FURAN DERIVATIVE FROM THE CHLOROFORM CRUDE EXTRACT OF Icacina trichantha oliv TUBER.\",\"authors\":\"O. U. Akoh, B. Anyanwu, O. M. Mac-Kalunta\",\"doi\":\"10.46602/jcsn.v49i1.956\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Spectroscopic analysis of a pure isolate (OAU 2, a furan derivative) by column chromatography from the chloroform crude extract of Icacina trichantha tuber was done using FT-IR, 1HNMR, 13CNMR, COSY and was established by literature as well as the investigation of antimycobacterial potency. This anitmycobacterial activity revealed that this isolate actually has activity against DR-TB Strain and H37RV Strain which are American type culture collection strain and multi-drug resistant strains of M. tuberculosis being the test organisms. Hence, confirming the folk believe of the use of I. trichantha tuber in the treatment of “serious cough”\",\"PeriodicalId\":15357,\"journal\":{\"name\":\"Journal Of Chemical Society Of Nigeria\",\"volume\":\"27 45\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-03-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal Of Chemical Society Of Nigeria\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46602/jcsn.v49i1.956\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal Of Chemical Society Of Nigeria","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46602/jcsn.v49i1.956","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
ISOLATION, CHARACTERIZATION AND ANTIMYCOBACTERIAL POTENCY OF A FURAN DERIVATIVE FROM THE CHLOROFORM CRUDE EXTRACT OF Icacina trichantha oliv TUBER.
Spectroscopic analysis of a pure isolate (OAU 2, a furan derivative) by column chromatography from the chloroform crude extract of Icacina trichantha tuber was done using FT-IR, 1HNMR, 13CNMR, COSY and was established by literature as well as the investigation of antimycobacterial potency. This anitmycobacterial activity revealed that this isolate actually has activity against DR-TB Strain and H37RV Strain which are American type culture collection strain and multi-drug resistant strains of M. tuberculosis being the test organisms. Hence, confirming the folk believe of the use of I. trichantha tuber in the treatment of “serious cough”
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