美国狂犬病疫苗接种的数学模型。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-03-21 DOI:10.1016/j.tpb.2024.03.004

Annalise Hassan , Zoe A. Tapp , Dan K. Tran , Jan Rychtář , Dewey Taylor

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引用次数: 0

摘要

狂犬病是最古老的病毒性疾病之一，除南极洲外，各大洲都曾出现过狂犬病。在美国，人类狂犬病病例非常罕见。在美国东部，浣熊是狂犬病的主要宿主，而宠物疫苗接种是防止人类感染狂犬病的重要屏障。在本文中，我们建立了一个狂犬病在浣熊和家养宠物之间传播的分区模型。我们找到了浣熊和家养宠物的无病平衡点和繁殖数量。我们还确定了实现消除狂犬病所需的浣熊和宠物疫苗接种率。

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Mathematical model of rabies vaccination in the United States

Rabies is one of the oldest viral diseases and it has been present on every continent except Antarctica. Within the U.S. human rabies cases are quite rare. In the eastern USA, raccoons are the main reservoir hosts and pet vaccination serves as an important barrier against human rabies exposure. In this paper, we develop a compartmental model for rabies transmission amongst raccoons and domestic pets. We find the disease-free equilibria, reproduction numbers for the raccoons and domestic pets. We also determine the vaccination coverage/rates, both for raccoons and pets, needed to achieve the elimination of rabies.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.