微生物合成促进健康的肌醇。

IF 7.1 2区工程技术 Q1 BIOCHEMICAL RESEARCH METHODS

Current opinion in biotechnology Pub Date : 2024-03-22 DOI:10.1016/j.copbio.2024.103114

Ken-ichi Yoshida , Michael Bott

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引用次数: 0

摘要

D-chiro-ositol 和 scyllo-ositol 因其促进健康的特性而闻名，有望成为功能食品的成分。通过代谢工程创造了枯草芽孢杆菌和谷氨酸棒状杆菌菌株，它们能够从肌醇（自然界中最常见的肌醇）中廉价生产这两种稀有肌醇。此外，通过进一步改造，还能从便宜得多的碳源葡萄糖或蔗糖中合成这两种稀有肌醇。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Microbial synthesis of health-promoting inositols

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Microbial synthesis of health-promoting inositols

D-chiro-inositol and scyllo-inositol are known for their health-promoting properties and promising as ingredients for functional foods. Strains of Bacillus subtilis and Corynebacterium glutamicum were created by metabolic engineering capable of inexpensive production of these two rare inositols from myo-inositol, which is the most common inositol in nature. In addition, further modifications have enabled the synthesis of the two rare inositols from the much-cheaper carbon sources, glucose or sucrose.

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来源期刊

Current opinion in biotechnology 工程技术-生化研究方法

CiteScore

16.20

自引率

2.60%

发文量

226

审稿时长

4-8 weeks

期刊介绍： Current Opinion in Biotechnology (COBIOT) is renowned for publishing authoritative, comprehensive, and systematic reviews. By offering clear and readable syntheses of current advances in biotechnology, COBIOT assists specialists in staying updated on the latest developments in the field. Expert authors annotate the most noteworthy papers from the vast array of information available today, providing readers with valuable insights and saving them time. As part of the Current Opinion and Research (CO+RE) suite of journals, COBIOT is accompanied by the open-access primary research journal, Current Research in Biotechnology (CRBIOT). Leveraging the editorial excellence, high impact, and global reach of the Current Opinion legacy, CO+RE journals ensure they are widely read resources integral to scientists' workflows. COBIOT is organized into themed sections, each reviewed once a year. These themes cover various areas of biotechnology, including analytical biotechnology, plant biotechnology, food biotechnology, energy biotechnology, environmental biotechnology, systems biology, nanobiotechnology, tissue, cell, and pathway engineering, chemical biotechnology, and pharmaceutical biotechnology.