[食物过敏的表型和内型]。

Ana Paula Beltrán Moschione Castro, Maria Belen Bossio
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引用次数: 0

摘要

食物过敏是一种常见病,尤其是在儿童群体中,约有 3%-6% 的儿童受到影响。食物过敏患者的护理面临着各种挑战,但可以肯定的是,症状的多样性和疾病的结果是治疗患者、制定护理指南和了解疾病自然史的重要方面。通过表型分类可以更好地了解食物过敏的演变过程。内型是表型的一种亚型,由其病理生理学特征定义。遗传、表观遗传和环境特征会干扰表型及其可能的内型的构建。了解食物过敏的表型和内型有两个基本方面:1) 需要了解对食物过敏的表型和内型进行分析将有助于确定预后,并有助于使用特定疗法进行干预,以及 2) 了解当地内型和表型特征的重要性,拉丁美洲不同国家的饮食多样性带来了各种可能造成过敏风险的食物,需要对这些食物进行研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Phenotypes and endotypes of food allergy].

Food allergy is a common event, especially in the pediatric population, affecting between 3-6% of children. There are various challenges in the care of patients with food allergy, but certainly the diversity of symptoms and the outcome of the disease are important aspects in the treatment of patients, in the development of care guidelines and in the knowledge of the Natural history of disease. The classification into phenotypes allows a better understanding of the evolution of food allergy. The endotype is a subtype of a phenotype defined by its pathophysiological characteristic. Genetic, epigenetic, and environmental characteristics interfere with the construction of the phenotype and its possible endotypes. Understanding the phenotypes and endotypes of food allergies brings with it two fundamental aspects: 1) the need to understand that the analysis of phenotypes and endotypes in food allergies will allow establishing prognoses and helping in intervention with specific therapies, and 2) the importance of understanding The characterization of local endotypes and phenotypes, and the dietary diversity of the different countries that make up Latin America brings with it a varied menu of foods that may pose a risk of allergy that needs to be studied.

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