右美沙芬诱发血清素综合征导致杀人和自杀的可能性。

Q4 Medicine

Academic Forensic Pathology Pub Date : 2024-01-30 eCollection Date: 2024-03-01 DOI:10.1177/19253621231224531

Matthew M Pavelka, Roland Kohr

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引用次数: 0

摘要

关于右美沙芬和选择性 5-羟色胺再摄取抑制剂超治疗量联合作用导致的 5-羟色胺综合征，已发表的病例报告非常有限。我们报告了一个青少年病例，该病例的尸检结果提示，血清素综合征引起的精神病诊断与双重凶杀和自杀有关。自杀者的尸检毒理学结果显示，一名 14 岁男性体内的氟西汀和右美沙芬的血清素代谢物明显升高。

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Potential Dextromethorphan-Induced Serotonin Syndrome Leading to Homicide and Suicide.

Limited case reports have been published regarding serotonin syndrome due to the combined effects of supratherapeutic levels of dextromethorphan and selective serotonin reuptake inhibitor. We report a case of an adolescent with postmortem findings suggestive of a diagnosis of serotonin syndrome-induced psychosis associated with a double homicide and suicide. Postmortem toxicology of the suicide victim was remarkable for elevated serotonergic metabolites of fluoxetine and dextromethorphan in a 14-year-old male.

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来源期刊

Academic Forensic Pathology Medicine-Pathology and Forensic Medicine

CiteScore

0.90

自引率

0.00%

发文量