角膜沉淀物：被忽视的小孢子菌基质角膜炎征兆？

IF 2.6 4区医学 Q2 OPHTHALMOLOGY

Ocular Immunology and Inflammation Pub Date : 2024-11-01 Epub Date: 2024-03-21 DOI:10.1080/09273948.2024.2329805

Ipsita Muni, Smruti Rekha Priyadarshini, Srikant Kumar Sahu, Sujata Das

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引用次数: 0

摘要

目的：阐明小孢子菌基质性角膜炎（MSK）病例的独特临床特征：方法：对2016年至2022年间通过角膜活检或宿主角膜扣针进行组织病理学和/或微生物学诊断为MSK的病例进行回顾性观察研究：结果：发现18例经组织病理学和/或微生物学确诊为MSK的病例。仔细查看裂隙灯照片发现，18 例病例中有 5 例（27.7%）在基质角膜炎区域之外存在色素性角膜沉淀（KPs）：结论：病变区域以外出现色素性角膜沉淀物可提醒临床医生将微孢子虫作为基质性角膜炎的一个鉴别病因。临床医生可据此采取相应的治疗措施，以获得更好的疗效。

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Keratic Precipitates: An Overlooked Sign of Microsporidial Stromal Keratitis?

Purpose: To elucidate a distinctive clinical feature in cases of microsporidial stromal keratitis (MSK).

Method: A retrospective observational study of cases with a histopathological and/or microbiological diagnosis of MSK on corneal biopsy or host corneal button between 2016 and 2022 was conducted.

Results: Eighteen cases with a confirmed histopathological and/or microbiological diagnosis of MSK were detected. Careful review of slit-lamp photographs revealed the presence of pigmented keratic precipitates (KPs) beyond the area of stromal keratitis in five out of eighteen cases (27.7%).

Conclusion: The presence of pigmented KPs beyond the area of lesion can alert the clinician to keep microsporidia as a differential cause for stromal keratitis. Management can be tailored accordingly for a better outcome.

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来源期刊

Ocular Immunology and Inflammation 医学-眼科学

CiteScore

6.20

自引率

15.20%

发文量

285

审稿时长

6-12 weeks

期刊介绍： Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.